N-(2,4-difluorophenyl)-N-isopropylcarbamoyl chloride | 212203-09-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2,4-difluorophenyl)-N-isopropylcarbamoyl chloride
• 英文别名: N-isopropyl-N-2,4-difluorophenylcarbamoyl chloride；N-(2,4-difluorophenyl)-N-propan-2-ylcarbamoyl chloride
• CAS: 212203-09-3
• 化学式: C₁₀H₁₀ClF₂NO
• 分子量: 233.645
• InChiKey: ZFJOSANCARMUBD-UHFFFAOYSA-N

物化性质

• 沸点：
  307.6±32.0 °C(Predicted)
• 密度：
  1.314±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-(2,4-difluorophenyl)-N-isopropylcarbamoyl chloride 、 1,2-二氢-3H-1,2,4-三氮唑-3-酮 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.0h， 以23%的产率得到N,N-bis(2,4-difluorophenyl)-N,N-diisopropyl-5-oxo-1,2,4-triazole-1,4-dicarboxamide
  参考文献：
  名称：

  1-(N,N-DISUBSTITUTED CARBAMOYL) 4-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVE, 4-(N,N-DISUBSTITUTED CARBAMOYL) 1-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT

  摘要：

  本发明提供了通式1所表示的1-(N,N-二取代氨基甲酰基) 4-(取代磺酰基)三唑林-5-酮衍生物，以及通式(11)所表示的4-(N,N-二取代氨基甲酰基) 1-(取代磺酰基)三唑林-5-酮衍生物，这些衍生物表现出优异的除草活性，并且含有这些衍生物作为活性成分的除草剂具有特定特性。在通式(1)中，R1-R4代表预定取代基。在通式(11)中，R11-R14代表预定取代基。

  公开号：

  US20200367499A1

文献信息

• 1-Substituted 4-carbamoyl-1,2,4-triazol-5-one derivatives and herbicide
  申请人：Hokko Chemical Industry Co., Ltd.

  公开号：US06077814A1

  公开（公告）日：2000-06-20

  A 1-phenyl, naphthyl or aralkyl-4-(N,N-di-substituted carbamoyl)-1,2,4-triazol-5-one derivative represented by the general formula (I) ##STR1## wherein A is an unsubstituted or substituted phenyl group, 1-naphthyl group, 5,6,7,8-tetrahydro-1-naphthyl group or an aralkyl group such as an unsubstituted or substituted benzyl group and so on, R.sub.1 is a lower alkyl group and so on, and R.sub.2 is an unsubstituted or substituted phenyl group and so on, was prepared as novel compounds. This 1-substituted-4-carbamoyl-1,2,4-triazol-5-one derivative does not substantially exhibit phytotoxicity to various agricultural crop plants and therefore is useful as a selective herbicide.

  通用公式（I）表示的一种1-苯基、萘基或烷基-4-(N,N-二取代氨基甲酰基)-1,2,4-三唑-5-酮衍生物，其中A是未取代或取代的苯基、1-萘基、5,6,7,8-四氢-1-萘基或烷基基团，如未取代或取代的苄基基团等，R.sub.1是低碳基基团等，R.sub.2是未取代或取代的苯基基团等，作为新型化合物制备。这种1-取代-4-氨基甲酰基-1,2,4-三唑-5-酮衍生物对各种农业作物基本不具有植物毒性，因此可用作选择性除草剂。
• 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE
  申请人：HOKKO CHEMICAL INDUSTRY CO. LTD.

  公开号：EP0974587A1

  公开（公告）日：2000-01-26

  A 1-phenyl, naphthyl or aralkyl-4-(N,N-di-substituted carbamoyl)-1,2,4-triazol-5-one derivative represented by the general formula (I) wherein A is an unsubstituted or substituted phenyl group, 1-naphthyl group, 5,6,7,8-tetrahydro-1-naphthyl group or an aralkyl group such as an unsubstituted or substituted benzyl group and so on, R1 is a lower alkyl group and so on, and R2 is an unsubstituted or substituted phenyl group and so on, was prepared as novel compounds. This 1-substituted-4-carbamoyl-1,2,4-triazol-5-one derivative does not substantially exhibit phytotoxicity to various agricultural crop plants and therefore is useful as a selective herbicide.

  由通式(I)代表的1-苯基、萘基或芳基-4-(N,N-二取代氨基甲酰基)-1,2,4-三唑-5-酮衍生物 其中 A 是未取代或取代的苯基、1-萘基、5,6,7,8-四氢-1-萘基或芳烷基，如未取代或取代的苄基等；R1 是低级烷基等；R2 是未取代或取代的苯基等。这种 1-取代-4-氨基甲酰基-1,2,4-三唑-5-酮衍生物对各种农作物植物没有实质性的植物毒性，因此可用作选择性除草剂。
• 1-(N,N-DISUBSTITUTED CARBAMOYL) 4-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVES, 4-(N,N-DISUBSTITUTED CARBAMOYL) 1-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVES, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT
  申请人：Hokko Chemical Industry Co., Ltd.

  公开号：EP3677573A1

  公开（公告）日：2020-07-08

  The present invention provides a 1-(N,N-disubstituted carbamoyl)4-(substituted sulfonyl)triazolin-5-one derivative represented by the following formula (1), a 4-(N,N-disubstituted carbamoyl) 1-(substituted sulfonyl)triazolin-5-one derivative represented by the following formula (11), each of which exhibits an excellent herbicidal activity, and a herbicide characterized by containing the derivative as an active ingredient. In the formula (1), R1 to R4 represent predetermined substituents, and in the formula (11), R11 to R14 represent predetermined substituents.

  本发明提供了下式(1)代表的 1-(N,N-二取代氨基甲酰基)4-(取代磺酰基)三唑啉-5-酮衍生物、下式(11)代表的 4-(N,N-二取代氨基甲酰基)1-(取代磺酰基)三唑啉-5-酮衍生物，它们都具有优异的除草活性，本发明还提供了一种除草剂，其特征在于含有该衍生物作为活性成分。 在式(1)中，R1 至 R4 代表预定取代基，在式(11)中，R11 至 R14 代表预定取代基。
• 1-(n,n-disubstituted carbamoyl) 4-(substituted sulfonyl)triazolin-5-one derivative, 4-(n,n-disubstituted carbamoyl) 1-(substituted sulfonyl)triazolin-5-one derivative, and herbicide containing said derivative as active ingredient
  申请人：HOKKO CHEMICAL INDUSTRY CO., LTD.

  公开号：US11076595B2

  公开（公告）日：2021-08-03

  The present invention provides a 1-(N,N-disubstituted carbamoyl)4-(substituted sulfonyl)triazolin-5-one derivative represented by the following formula (1), a 4-(N,N-disubstituted carbamoyl)1-(substituted sulfonyl)triazolin-5-one derivative represented by the following formula (11), each of which exhibits an excellent herbicidal activity, and a herbicide characterized by containing the derivative as an active ingredient: wherein in the formula (1), R1 to R4 represent predetermined substituents, and in the formula (11), R11 to R14 represent predetermined substituents.

  本发明提供了下式(1)代表的 1-(N,N-二取代氨基甲酰基)4-(取代磺酰基)三唑啉-5-酮衍生物、下式(11)代表的 4-(N,N-二取代氨基甲酰基)1-(取代磺酰基)三唑啉-5-酮衍生物，它们都具有优异的除草活性，本发明还提供了一种除草剂，其特征在于含有该衍生物作为活性成分： 其中，在式 (1) 中，R1 至 R4 代表预定取代基，在式 (11) 中，R11 至 R14 代表预定取代基。
• JPH10251238A
  申请人：——

  公开号：JPH10251238A

  公开（公告）日：1998-09-22