r-1,cis-2(a),trans-6(e)-triphenyl-4-phosphorinanone | 76189-76-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: r-1,cis-2(a),trans-6(e)-triphenyl-4-phosphorinanone
• 英文别名: 1,2,6-triphenyl-4-phosphorinanone；(2R,6R)-1,2,6-Triphenyl-phosphinan-4-one；(2R,6R)-1,2,6-triphenylphosphinan-4-one
• CAS: 76189-76-9
• 化学式: C₂₃H₂₁OP
• 分子量: 344.393
• InChiKey: LQWINIIHGWXQCK-DHIUTWEWSA-N

物化性质

• 熔点：
  173-174 °C
• 沸点：
  524.1±50.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  r-1,cis-2(a),trans-6(e)-triphenyl-4-phosphorinanone 在 sulfur 作用下， 以 苯 为溶剂， 反应 4.0h， 以35.6%的产率得到r-1,cis-2(a),trans-6(e)-triphenyl-4-phosphorinanone 1-sulfide
  参考文献：
  名称：

  Carbon-phosphorus heterocycles. Conformational analysis of substituted 1-phenyl-4-phosphorinanones and derivatives. Single-crystal x-ray diffraction analysis of 1-r,cis-2a,trans-6e-triphenyl-4-phosphorinanone 1-sulfide

  摘要：

  DOI：

  10.1021/jo00319a023
• 作为产物：
  描述：

  苯基膦 以 吡啶 为溶剂， 反应 8.0h， 生成 r-1,cis-2(a),trans-6(e)-triphenyl-4-phosphorinanone
  参考文献：
  名称：

  Carbon-phosphorus heterocycles. Conformational analysis of substituted 1-phenyl-4-phosphorinanones and derivatives. Single-crystal x-ray diffraction analysis of 1-r,cis-2a,trans-6e-triphenyl-4-phosphorinanone 1-sulfide

  摘要：

  DOI：

  10.1021/jo00319a023

文献信息

• Palladacycle-Catalyzed Asymmetric Intermolecular Construction of Chiral Tertiary P-Heterocycles by Stepwise Addition of H–P–H Bonds to Bis(enones)
  作者：Yinhua Huang、Sumod A. Pullarkat、Siewping Teong、Renta Jonathan Chew、Yongxin Li、Pak-Hing Leung

  DOI：10.1021/om300405h

  日期：2012.7.9

  A palladacycle-catalyzed diastereo- and enantio-selective stepwise double hydrophosphination of bis(enones) with PhPH2 has been developed, allowing intermolecular construction of chiral tertiary bulky P-heterocycles in one pot in high yields. A catalytic cycle for the reaction is proposed as well.
• Novel thermal-catalyzed isomerization of certain substituted 1,2,6-triphenyl-4-phosphorinanones. Stereochemical and conformational analysis of substituted 1,2,6-triphenyl-4-phosphorinanones and 2,6-diphenyl-4-thianones via ultraviolet spectrometry, carbon-13 NMR spectroscopy, and liquid crystal circular dichroism spectropolarimetry
  作者：Jang B. Rampal、Nagichettiar Satyamurthy、John M. Bowen、Neil Purdie、K. Darrell Berlin

  DOI：10.1021/ja00415a031

  日期：1981.12
• RAMPAL, J. B.;SATYAMURTHY, NAGICHETTIAR;BOWEN, J. M.;PURDIE, N.;BERLIN, K+, J. AMER. CHEM. SOC., 1981, 103, N 25, 7602-7609
  作者：RAMPAL, J. B.、SATYAMURTHY, NAGICHETTIAR、BOWEN, J. M.、PURDIE, N.、BERLIN, K+

  DOI：——

  日期：——
• Carbon-phosphorus heterocycles. Conformational analysis of substituted 1-phenyl-4-phosphorinanones and derivatives. Single-crystal x-ray diffraction analysis of 1-r,cis-2a,trans-6e-triphenyl-4-phosphorinanone 1-sulfide
  作者：Jang B. Rampal、Gary D. Macdonell、James P. Edasery、K. Darrell Berlin、Asadur Rahman、Dick Van der Helm、K. Michal Pietrusiewicz

  DOI：10.1021/jo00319a023

  日期：1981.3