1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluorononane | 168834-06-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluorononane
• CAS: 168834-06-8
• 化学式: F(CF₂)₆(CH₂)₃H
• 分子量: 362.13
• InChiKey: INWWPBCQHLHWRD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  13

文献信息

• Lubricant for improved gliding properties of skis
  申请人：Centeiro Trading LDA

  公开号：EP0940465A1

  公开（公告）日：1999-09-08

  The present invention concerns a lubricant for improving the gliding properties of skis. The objective of the invention is to propose a lubricant presenting an elevated molecular weight but with a very low melting point. Furthermore the lubricant is not to crystallise easily and thus to remain oily or waxy also at low temperatures. For meeting these objectives the lubricant is constituted of four perfluorinated chains attached to a hydrogenated core in a symmetrical arrangement in such a manner that a tetrakis derivative is formed according to the following formula

  本发明涉及一种用于改善滑雪板滑行性能的润滑剂。 本发明的目的是提出一种分子量较高但熔点很低的润滑剂。此外，这种润滑剂不易结晶，因此在低温下也能保持油性或蜡性。 为了实现这些目标，润滑剂由四条全氟链组成，这些全氟链以对称排列的方式连接到氢化芯上，从而形成四烷基衍生物，其式如下
• Aminoalcohol lipidoids and uses thereof
  申请人：Massachusetts Institute of Technology

  公开号：US10189802B2

  公开（公告）日：2019-01-29

  Aminoalcohol lipidoids are prepared by reacting an amine with an epoxide-terminated compound are described. Methods of preparing aminoalcohol lipidoids from commercially available starting materials are also provided. Aminoalcohol lipidoids may be prepared from racemic or stereochemically pure epoxides. Aminoalcohol lipidoids or salts forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these aminoalcohol lipidoid compounds, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive lipidoids and polynucleotide have been prepared. The inventive lipidoids may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.

  本文介绍了通过胺与环氧化物封端化合物反应制备氨基醇脂质的方法。还提供了从市售起始原料制备氨基醇类脂质的方法。氨基醇脂质可由外消旋或立体化学纯环氧化物制备。氨基醇类脂质或其盐类最好具有生物降解性和生物相容性，可用于各种给药系统。考虑到这些氨基醇类脂化合物的氨基，它们特别适合用于多核苷酸的给药。现已制备出含有本发明类脂化合物和多核苷酸的复合物、胶束、脂质体或颗粒。本发明的类脂质还可用于制备给药微粒。由于本发明脂质具有缓冲周围环境 pH 值的能力，因此在递送易变药剂方面特别有用。
• Biodegradable lipids for delivery of nucleic acids
  申请人：Translate Bio, Inc.

  公开号：US10286083B2

  公开（公告）日：2019-05-14

  The present invention provides, in part, a biodegradable compound of formula I, and sub-formulas thereof: Formula (I) or a pharmaceutically acceptable salt thereof, where each X independently is O or S, each Y independently is O or S, and each R1 independently is defined herein; and a liposome composition comprising the cationic lipid of formula I or a sub-formula thereof, and methods of delivering agents, such as nucleic acids including mRNA, in vivo, by administering to a subject the liposome comprising the cationic lipid of formula I or a sub-formula thereof, where the agent is encapsulated within the liposome.

  本发明部分提供了一种可生物降解的式 I 及其子式化合物：式(I)或其药学上可接受的盐，其中每个X独立地为O或S，每个Y独立地为O或S，每个R1独立地在本文中定义；以及包含式I阳离子脂质或其亚式的脂质体组合物，以及通过向受试者施用包含式I阳离子脂质或其亚式的脂质体的脂质体在体内递送药剂（如核酸，包括mRNA）的方法，其中药剂被包裹在脂质体内。
• Method for manufacturing structure having recessed pattern, resin composition, method for forming electroconductive film, electronic circuit, and electronic device
  申请人：JSR CORPORATION

  公开号：US10392699B2

  公开（公告）日：2019-08-27

  The present invention relates to: a method of producing a structure having a recessed pattern; a resin composition; a method of forming an electroconductive film; an electronic circuit; and an electronic device. The method of producing a structure having a recessed pattern includes the following steps (i) and (ii), and the recessed pattern has a film thickness that is thinner by 5% to less than 90% with respect to that of a coating film obtained in the step (i): (i) the step of forming a coating film on a non-flat surface of a structure using a resin composition which includes an acid-dissociable group-containing polymer and an acid generator; and (ii) the step of forming a recess by subjecting a prescribed part of a portion of the coating film to irradiation with radiation.

  本发明涉及：一种生产具有凹陷图案的结构的方法；一种树脂组合物；一种形成导电薄膜的方法；一种电子电路；以及一种电子设备。生产具有凹陷图案的结构的方法包括以下步骤(i)和(ii)，凹陷图案的薄膜厚度比步骤(i)中获得的涂膜薄 5%至小于 90%： (i) 使用树脂组合物在结构的非平面上形成涂膜的步骤，该树脂组合物包括含酸可分解基团的聚合物和酸生成物；以及 (ii) 通过对涂膜部分的规定部分进行辐射形成凹槽的步骤。
• METHOD FOR FORMING PATTERNS AND METHOD FOR PRODUCING PATTERNED SUBSTRATES
  申请人：FUJIFILM CORPORATION

  公开号：US20130032971A1

  公开（公告）日：2013-02-07

  A resist layer constituted by a resist composition (which may include unavoidable impurities) including a polymerizable compound that includes polyfunctional monomers that become polymers having three dimensional structures by cross linking when polymerized and a polymerization initiating agent which is activated by one of light and an electron beam is formed on a substrate. A surface of a mold having a predetermined pattern of protrusions and recesses is pressed against the resist layer. Light is irradiated onto the resist layer to cure the resist layer. The mold is separated from the resist layer under conditions that the temperature of the resist layer is 40° C. or greater.