1-(4-Bromophenyl)violuric acid [WHO-DD] | 251468-56-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1-(4-Bromophenyl)violuric acid [WHO-DD]
• 英文别名: 1-(4-bromophenyl)-6-hydroxy-5-nitrosopyrimidine-2,4-dione
• CAS: 251468-56-1
• 化学式: C₁₀H₆BrN₃O₄
• 分子量: 312.08
• InChiKey: KLAOPOKEJSDMEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  99.1
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• DRUG FOR TREATING LIVER LESIONS CAUSED BY THE ACTION OF CHEMICAL OR BIOLOGICAL AGENTS
  申请人：Tets, Viktor Veniaminovich

  公开号：EP2638900A1

  公开（公告）日：2013-09-18

  The invention relates to medicine and can be used for treating liver lesions caused by chemical or biological agents. The drug for treating liver lesions caused by chemical or biological agents is embodied as 1-(4-bromophenyl)-6-hydroxy-5-nitroso-1,2,3,4-tetrahydropyrimidine-2.4-dione: (I), or salts thereof having the general formula: (II), where X is selected from Na+, K+, Li+, NH4+,NH2CONH3+ or another pharmacologically acceptable cation. The effectiveness of the preparation in treating liver diseases of different etiologies is increased.

  本发明涉及药物，可用于治疗化学或生物制剂引起的肝脏病变。治疗化学或生物制剂引起的肝脏病变的药物体现为 1-(4-溴苯基)-6-羟基-5-亚硝基-1,2,3,4-四氢嘧啶-2.4-二酮：(I)或其具有通式的盐：(II)，其中 X 选自 Na+、K+、Li+、NH4+、NH2CONH3+ 或其他药理上可接受的阳离子。本制剂在治疗不同病因引起的肝脏疾病方面的疗效均有所提高。
• Drug for Treating Liver Lesions Caused by the Action of Chemical or Biological Agents
  申请人：Tets Viktor Veniaminovich

  公开号：US20130237704A1

  公开（公告）日：2013-09-12

  The invention relates to medicine and can be used for treating liver lesions caused by chemical or biological agents. The drug for treating liver lesions caused by chemical or biological agents is embodied as 1-(4-bromophenyl)-6-hydroxy-5-nitroso-1,2,3,4-tetrahydropyrimidine-2.4-dione: (I), or salts thereof having the general formula: (II), where X is selected from Na + , K + , Li + , NH 4 + , NH 2 CONH 3 + or another pharmacologically acceptable cation. The effectiveness of the preparation in treating liver diseases of different etiologies is increased.
• US8999959B2
  申请人：——

  公开号：US8999959B2

  公开（公告）日：2015-04-07
• [EN] DRUG FOR TREATING LIVER LESIONS CAUSED BY THE ACTION OF CHEMICAL OR BIOLOGICAL AGENTS<br/>[FR] MÉDICAMENT POUR LE TRAITEMENT DE LÉSIONS HÉPATIQUES PROVOQUÉES PAR DES AGENTS CHIMIQUES OU BIOLOGIQUES
  申请人：TETS VIKTOR VENIAMINOVICH

  公开号：WO2012064221A1

  公开（公告）日：2012-05-18

  Изобретение относится к медицине и может быть использовано для лечения поражений печени вызванных химическими или биологическими агентами. Средство для лечения поражений печени, вызванных воздействием химических или биологических агентов, представляет собой 1-(4-бромфенил)-6- гидрокси-5-нитрозо-1,2,3,4-тетрагидро-пиримидин-2.4-дион: (I), или его соли общей формулы: (II), где X выбран из ряда: Na+, К+, Li+, NH4+,NH2CONH3+ или другой фармакологически приемлемый катион. Повышается эффективность препарата для лечения заболеваний печени различного генеза.