1-(adamantan-1-ylmethyl)thiourea | 65069-67-2

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫脲类
• 英文名称: 1-(adamantan-1-ylmethyl)thiourea
• 英文别名: 1-((adamantan-lyl)methyl)thiourea；1-Adamantylmethylthiourea
• CAS: 65069-67-2
• 化学式: C₁₂H₂₀N₂S
• 分子量: 224.37
• InChiKey: OLNMWJVNWXUTLA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  39.4
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• ANTIVIRAL COMPOUNDS AND USE THEREOF
  申请人：UNIVERSITA DEGLE STUDI DI SIENA

  公开号：US20210070737A1

  公开（公告）日：2021-03-11

  The present invention relates to compounds of formula (I), their use as medicaments, in particular as broad spectrum antiviral agents, their combination with a further antiviral agent and relative pharmaceutical compositions. In particular, the compounds of the invention are useful in the treatment of a disease caused by an enveloped virus.
• US4211867A
  申请人：——

  公开号：US4211867A

  公开（公告）日：1980-07-08
• [EN] COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA<br/>[FR] COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE LA MALARIA
  申请人：UNIV SAINT LOUIS

  公开号：WO2014160775A1

  公开（公告）日：2014-10-02

  The present invention provides aminohydantoin anti-malarial agents. In some embodiments, these agents have the property of functions of targeting malarial aspartic proteases while at the same time having low activity against human BACE. Methods of employing such agents are also provided.