[3-[[3-[(2-Bromoacetyl)amino]phenoxy]-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl [3-[(2-bromoacetyl)amino]phenyl] hydrogen phosphate

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷酸
• 英文名称: [3-[[3-[(2-Bromoacetyl)amino]phenoxy]-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl [3-[(2-bromoacetyl)amino]phenyl] hydrogen phosphate
• 化学式: C₂₆H₂₈Br₂N₄O₁₃P₂
• 分子量: 826.3
• InChiKey: FOMCMPPVDCKFJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  47
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  228
• 氢给体数：
  5
• 氢受体数：
  13

文献信息

• SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE NEURONAL CELLS
  申请人：The J. David Gladstone Ins., a testamentary trust established under the Will of J. David Gladstone

  公开号：US20160250260A1

  公开（公告）日：2016-09-01

  Compositions and methods are described herein for chemically inducing cells to change their differentiation state and become neuronal cells.