1.2-Bis-(ethyl-mercapto)-propan | 54410-62-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 1.2-Bis-(ethyl-mercapto)-propan
• 英文别名: 1.2-Diethyl-mercapto-propan；1,2-bis-ethylsulfanyl-propane；1,2-bis(ethylthio)-propane；Propane, 1,2-bis(ethylthio)-；1,2-bis(ethylsulfanyl)propane
• CAS: 54410-62-7；34391-86-1
• 化学式: C₇H₁₆S₂
• 分子量: 164.336
• InChiKey: PSZPWGIXOWMYHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-(ethylthio)propene 、 乙硫醇 生成 1.2-Bis-(ethyl-mercapto)-propan
  参考文献：
  名称：

  Shostakovskii,M.F. et al., Journal of general chemistry of the USSR, 1960, vol. 30, p. 407 - 411

  摘要：

  DOI：

文献信息

• Use of asafetida extract as medicine for abstinence of drugs
  申请人：Wang Zemin

  公开号：US20060078570A1

  公开（公告）日：2006-04-13

  The present invention relates to the use of asafetida extract in the preparation of medicine for abstinence of drugs. The present invention further relates to a method for abstinence of drugs, which comprises administering a therapeutically effective amount of asafetida extract to subjects. The asafetida extract according to the present invention may be extracted from factice resin of Ferula sinkiangensis K.M. Shen or Ferula fukanensis K.M. Shen, and consists essentially of α-pinene, α-terpinene, 2-borneol, terpin-4-ol, D-fenchyl alcohol, pinocarveol, β-ocimene A, β-ocimene B, di-sec-butyl disulfide, sec-butyl-trans-1-butenyl disulfide, sec-butyl-cis-propenyl disulfide, sec-butyl-cis-1-butenyl disulfide, sec-butyl-trans-2-butenyl disulfide and thio-sec-butyl-trans-methylethenyl disulfide. The asafetida extract according to the present invention may also be extracted from factice resin of F. assafoetida L from Iran, Afghanistan and the like, and consists essentially of α-pinene, 2-borneol, terpin-4-ol, D-fenchyl alcohol, pinocarveol, dimethyl disulfide, dimethyl trisulfide, methylpropenyl disulfide, 2,2-dimethylthiopropane, 1,2-diethylthiopropane, N,N-dimethylthioformamide and propenylbutyl disulfide. The medicine for abstinence of drugs prepared with asafetida extract according to the present invention is suitable for the use in the abstinence treatment of subjects addicted to opioid, morphine, marijuana, diamorphine and the like.

  本发明涉及asafetida提取物在制备戒毒药物中的用途。本发明进一步涉及一种戒除毒品的方法，该方法包括向受试者施用治疗有效量的asafetida提取物。根据本发明，asafetida 提取物可从以下植物的糠醛树脂中提取 阿魏 沈国明或 呋喃阿魏 K.M. Shen主要成分有α-蒎烯、α-萜品烯、2-龙脑、萜品-4-醇、D-葑醇、蒎烷醇、β-ocimene A、β-ocimene B、二-仲丁基二硫化物、仲丁基-反式-1-丁烯基二硫醚、仲丁基-顺式-丙烯基二硫醚、仲丁基-顺式-1-丁烯基二硫醚、仲丁基-反式-2-丁烯基二硫醚和硫代仲丁基-反式-甲基乙烯基二硫醚。本发明中的阿沙飞陀提取物也可以从阿沙飞陀的树脂中提取。 F. assafoetida 本发明的asafetida提取物也可以从伊朗、阿富汗等地的Factice树脂中提取，主要成分为α-蒎烯、2-龙脑、萜品-4-醇、D-葑醇、蒎烷醇、二甲基二硫化物、二甲基三硫化物、甲基丙烯基二硫化物、2,2-二甲基硫代丙烷、1,2-二乙基硫代丙烷、N,N-二甲基硫代甲酰胺和丙烯基丁基二硫化物。根据本发明，用 Asafetida 提取物制备的戒毒药物适用于对阿片类、吗啡、大麻、二吗啡等成瘾者的戒毒治疗。
• The Addition of Thiyl Radicals to Allenic Hydrocarbons¹
  作者：Thomas L. Jacobs、G. E. Illingworth

  DOI：10.1021/jo01045a048

  日期：1963.10
• IMMOBILISED BIOLOGICAL ENTITIES
  申请人：Leontein Karin

  公开号：US20120231043A1

  公开（公告）日：2012-09-13

  There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da (ii) a total molecular weight of 1,500 to 1,000,000 Da (iii) a ratio of total molecular weight to core moiety molecular weight of at least 80:1 and (iv) functional end groups, whereby one or more of said functional end groups have an anti-coagulant entity covalently attached thereto.
• US5066778A
  申请人：——

  公开号：US5066778A

  公开（公告）日：1991-11-19
• US7288269B2
  申请人：——

  公开号：US7288269B2

  公开（公告）日：2007-10-30