Furan-3-yl-[2-(hydroxymethyl)-1,3-dimethylcyclohex-3-en-1-yl]methanol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: Furan-3-yl-[2-(hydroxymethyl)-1,3-dimethylcyclohex-3-en-1-yl]methanol
• 化学式: C₁₄H₂₀O₃
• 分子量: 236.311
• InChiKey: UGNKKOBPMCIIEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  53.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  梣酮 在 sodium tetrahydroborate 作用下， 以 乙醇 为溶剂， 反应 30.0h， 以140 mg的产率得到(3R,3aR)-3-(furan-3-yl)-3a,7-dimethyl-3,4,5,6,7,7a-hexahydro-2-benzofuran-1-one
  参考文献：
  名称：

  Antifungal alkaloids and limonoid derivatives from Dictamnus dasycarpus

  摘要：

  From the root bark of Dictamnus dasycarpus (Rutaceae), four limonoid derivatives, two furoquinoline alkaloids, five limonoids, two sesquiterpenes and three steroids were isolated and their structures elucidated on the basis of various spectroscopic methods. Among the identified compounds, one was determined to be a new natural product, 6 beta-hydroxyfraxinellone, while six compounds were found to be active against the plant pathogenic fungus Cladosporium cucumerinum. The relationship between the structures of limonoid derivatives and their inhibitory activity against fungal growth was investigated. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0031-9422(97)00541-4