2-Methyl-5-(4-trifluoromethyl-phenylamino)-benzothiazole-4,7-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Methyl-5-(4-trifluoromethyl-phenylamino)-benzothiazole-4,7-dione
• 英文别名: 2-Methyl-5-{[4-(trifluoromethyl)phenyl]amino}benzothiazole-4,7-dione；2-methyl-5-[4-(trifluoromethyl)anilino]-1,3-benzothiazole-4,7-dione
• 化学式: C₁₅H₉F₃N₂O₂S
• 分子量: 338.31
• InChiKey: ALXOAVPKCQEGSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  87.3
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  对三氟甲基苯胺 、 5-甲氧基-2-甲基-4,7-苯并噻唑二酮 以 乙醇 为溶剂， 反应 5.0h， 生成 2-Methyl-5-(4-trifluoromethyl-phenylamino)-benzothiazole-4,7-dione
  参考文献：
  名称：

  Synthesis and antifungal activities of 5/6-arylamino-4,7-dioxobenzothiazoles

  摘要：

  5/6-Arylamino-4,7 -dioxobenzothiazoles were synthesized and tested for in vitro antifungal activities against pathogenic fungi. Most of the tested 4,7-dioxobenzothiazoles exhibited potent antifungal activities against Candida species and Aspergillus niger (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(00)00301-2

文献信息

• Synthesis and antifungal activities of 5/6-arylamino-4,7-dioxobenzothiazoles
  作者：Chung-Kyu Ryu、Hye-Young Kang、Yu-Jin Yi、Keun-Hwa Shin、Byung-Hoon Lee

  DOI：10.1016/s0960-894x(00)00301-2

  日期：2000.7

  5/6-Arylamino-4,7 -dioxobenzothiazoles were synthesized and tested for in vitro antifungal activities against pathogenic fungi. Most of the tested 4,7-dioxobenzothiazoles exhibited potent antifungal activities against Candida species and Aspergillus niger (C) 2000 Elsevier Science Ltd. All rights reserved.