trans-4-octene | 1312412-37-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trans-4-octene
• 英文别名: (E)-benzyl hydroxy(oct-5-en-4-yl)carbamate；benzyl N-hydroxy-N-[(E)-oct-5-en-4-yl]carbamate
• CAS: 1312412-37-5
• 化学式: C₁₆H₂₃NO₃
• 分子量: 277.364
• InChiKey: KYDPHIKWHKKRQR-LFYBBSHMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  20
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-(苄羰氧基)羟基胺 、 反-4-辛烯 在 吡啶 、 copper(l) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 45.0h， 生成 trans-4-octene 、 trans-4-octene
  参考文献：
  名称：

  Copper-Catalyzed Aerobic Oxidation of Hydroxamic Acids Leads to a Mild and Versatile Acylnitroso Ene Reaction

  摘要：

  A mild formation of transient acylnitroso intermediates using a copper chloride catalyst and 1 atm of air as the terminal oxidant is described. The mild reaction conditions enable the inter- and intramolecular acylnitroso ene reaction with a wide range of functionalized alkene partners, as well as the first asymmetric variant. Notably, this transformation provides a practical and operationally simple method for effecting allylic amidation using an environmentally benign oxidant and a readily abundant transition metal.

  DOI：

  10.1021/ja204603u

文献信息

• Copper-Catalyzed Aerobic Oxidation of Hydroxamic Acids Leads to a Mild and Versatile Acylnitroso Ene Reaction
  作者：Charles P. Frazier、Jarred R. Engelking、Javier Read de Alaniz

  DOI：10.1021/ja204603u

  日期：2011.7.13

  A mild formation of transient acylnitroso intermediates using a copper chloride catalyst and 1 atm of air as the terminal oxidant is described. The mild reaction conditions enable the inter- and intramolecular acylnitroso ene reaction with a wide range of functionalized alkene partners, as well as the first asymmetric variant. Notably, this transformation provides a practical and operationally simple method for effecting allylic amidation using an environmentally benign oxidant and a readily abundant transition metal.