Tetrahydrofuran, 2-(2-hydroxyethoxy)

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢呋喃
• 英文名称: Tetrahydrofuran, 2-(2-hydroxyethoxy)
• 英文别名: 2-(oxolan-2-yloxy)ethanol
• 化学式: C₆H₁₂O₃
• 分子量: 132.16
• InChiKey: OJLQUVQAMKEDTB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Pyrazolopyrimidine Derivative
  申请人：Kashiwagi Toshihiko

  公开号：US20090234117A1

  公开（公告）日：2009-09-17

  A pyrazolopyrimidine derivative of the formula [I] wherein R 1 is an optionally substituted aromatic ring group, an optionally substituted lower alkyl group or an optionally substituted amino group; R 2 is an optionally substituted aromatic ring group; R 3 is an optionally substituted lower alkyl group; and R 4 is a hydrogen atom, a lower alkyl group, a halogen atom, a nitro group or an amino group; or a pharmaceutically acceptable salt thereof is useful as an antagonist of CRF receptor.

  公式[I]中的吡唑吡嗪衍生物，其中R1是可选取代的芳香环基团、可选取代的较低烷基团或可选取代的氨基团；R2是可选取代的芳香环基团；R3是可选取代的较低烷基团；R4是氢原子、较低烷基团、卤原子、硝基或氨基团；或其药学上可接受的盐，可用作CRF受体拮抗剂。
• Heterocyclic compounds
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0256266A2

  公开（公告）日：1988-02-24

  Intermediates for heterocyclic compounds having fungicidal or plant growth regulatory activity are compounds having the general formula (II): and stereoisomers thereof, wherein: Q is phenyl or aralkyl having one to four carbon atoms in the alkyl moiety, optionally substituted with one or more substituents selected from halogen, haloalkyl, C1-4alkyl, C1-4 alkoxy, phenyl and phenoxy; or Q is C1-6alkyl; R², R³, R⁴, R⁵ and R⁶, which may be the same or different, is each H, C1-6alkyl, C3-6cycloalkyl, or is phenyl or aralkyl having one to four carbon atoms in the alkyl moiety, optionally substituted with one or more substituents selected from halogen, haloalkyl, C1-4alkyl, C1-4alkoxy, phenyl and phenoxy; and R⁷ and R⁸, which may be the same or different, are alkyl or alkenyl groups or together form a ring. Other compounds and their use in preparing compounds of general formula (II) are described.

  具有杀菌或植物生长调节活性的杂环化合物的中间体是通式（II）的化合物： 及其立体异构体，其中 Q 是苯基或在烷基中含有一至四个碳原子的芳烷基，可任选被一个或多个选自卤素、卤代烷基、C1-4 烷基、C1-4 烷氧基、苯基和苯氧基的取代基取代； 或 Q 是 C1-6 烷基； R²、R³、R⁴、R⁵ 和 R⁶（可以相同或不同）各自是 H、C1-6 烷基、C3-6 环烷基，或者是苯基或在烷基中具有一至四个碳原子的芳烷基，可选择被一个或多个选自卤素、卤代烷基、C1-4 烷基、C1-4 烷氧基、苯基和苯氧基的取代基取代；以及 R⁷ 和 R⁸ 可以相同或不同，均为烷基或烯基，或共同形成一个环。 本文还描述了其他化合物及其在制备通式（II）化合物中的用途。
• Dye-containing negative working curable composition, color filter and production method thereof
  申请人：Takakuwa Hideki

  公开号：US20070212623A1

  公开（公告）日：2007-09-13

  The invention provides a dye-containing negative working curable composition comprising at least a dye, a photopolymerization initiator, a polymerizable monomer, and a colorless compound having a number average molecular weight of 1,000 to 5,000, wherein the ratio of an alkali-soluble resin to the total solid content of the composition is 10% by mass or less.
• Solubilized formulation of docetaxel without tween 80
  申请人：Palepu Nageswara R.

  公开号：US20080319048A1

  公开（公告）日：2008-12-25

  Lyophilizates containing docetaxel and the use thereof in preparing concentrated liquid formulations, and ready to use formulations for injection, as well as such concentrates and ready to use formulations themselves are disclosed in which Tween surfactants are avoided so that hypersensitivity reactions to Tween surfactants can be avoided and docetaxel can be administered at higher doses and/or for longer periods of time and/or for additional treatment cycles.
• Solubilized formulation of docetaxel
  申请人：Palepu Nageswara R.

  公开号：US20110092579A1

  公开（公告）日：2011-04-21

  Docetaxel containing formulations having TPGS and being substantially free or totally free of polysorbate surfactants are disclosed wherein stability is enhanced and hypersensitivity reactions are reduced.