2,2-Dimethyl-4,5-dithiahexane

• 分子结构分类: 有机化合物 - 有机硫化合物 - 有机二硫化物
• 英文名称: 2,2-Dimethyl-4,5-dithiahexane
• 英文别名: 2,2-dimethyl-1-(methyldisulfanyl)propane
• 化学式: C₆H₁₄S₂
• 分子量: 150.3
• InChiKey: UUFBJRBAPHQZBB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONOTHIOLATES AND -PHOSPHONATES<br/>[FR] CONJUGAISON CHIMIOSÉLECTIVE D'UN THIOL AVEC DES ALCÈNE- OU ALCYNE-PHOSPHONOTHIOLATES ET -PHOSPHONATES
  申请人：FORSCHUNGSVERBUND BERLIN EV

  公开号：WO2019170710A2

  公开（公告）日：2019-09-12

  Disclosed are novel conjugates and processes for the preparation thereof. A process for the preparation of alkene-or alkyne-phosohonothiolates and -phosphonates comprises the step of: reacting a compound of formula (I) with a thiol-containing molecule of formula (II) wherein represents an amino acid, a peptide, a protein, an antibody, a nucleotide, an oligonucleotide, a saccharide, a polysaccharide, a polymer, an optionally substituted C1-C8-alkyl, an optionally substituted phenyl, or an optionally substituted aromatic 5-or 6- membered heterocyclic system; resulting in a compound of formula (III)..