5-Isopropyl-2,2-dimethyltetrahydrofuran

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢呋喃
• 英文名称: 5-Isopropyl-2,2-dimethyltetrahydrofuran
• 英文别名: 2,2-dimethyl-5-propan-2-yloxolane
• 化学式: C₉H₁₈O
• 分子量: 142.24
• InChiKey: APTGZQDPKDMKGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• HETEROCYCLIC TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR
  申请人：AMGEN INC.

  公开号：US20170320860A1

  公开（公告）日：2017-11-09

  Compounds of Formula I and Formula II, pharmaceutically acceptable salts thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.

  公式I和公式II的化合物，其药用盐，上述任何一个的立体异构体，或它们的混合物是APJ受体的激动剂，可能用于治疗心血管和其他疾病。公式I和公式II的化合物具有以下结构： 其中变量的定义在此提供。
• CATALYSTS FOR HYDRODEOXYGENATION OF OXYGENATED HYDROCARBONS
  申请人：Blank Brian

  公开号：US20140051872A1

  公开（公告）日：2014-02-20

  The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing palladium, molybdenum, tin, and tungsten. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.

  本发明提供了将含氧碳氢化合物转化为含氧化合物的催化剂、方法和反应器系统。该发明包括利用含有钯、钼、锡和钨的催化剂从含氧碳氢化合物（如碳水化合物、糖类、糖醇、糖降解产物等）生产环氧醚、单氧化物、双氧化物、酮、醛、羧酸和醇的方法。生产的含氧化合物可用于生产液体燃料、化学品和其他产品。
• BICYCLIC HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION
  申请人：Bruce Ian

  公开号：US20130237519A1

  公开（公告）日：2013-09-12

  Bicyclic heterocyclic derivatives of formula I useful in inhibiting PDGF receptor mediated biological activity. wherein A is and R 1 , R 1a , R 2 , R 3 , R 4 , R 5 , R 6 and X are as defined herein.

  具有以下公式I的双环杂环衍生物可用于抑制PDGF受体介导的生物活性。其中A为，R1，R1a，R2，R3，R4，R5，R6和X如下所定义。
• Catalysts for hydrodeoxygenation of oxygenated hydrocarbons
  申请人：VIRENT, INC.

  公开号：US10131604B2

  公开（公告）日：2018-11-20

  The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing Group VIII metals. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.

  本发明提供了将含氧烃转化为含氧化合物的催化剂、方法和反应器系统。本发明包括使用含第八族金属的催化剂，从含氧烃（如碳水化合物、糖、糖醇、糖降解产物等）生产环醚、一氧 化物、二氧 化物、酮、醛、羧酸和醇的方法。生成的含氧化合物可用于生产液体燃料、化学品和其他产品。
• INHIBITING (ALPHA-V)(BETA-6) INTEGRIN
  申请人：Morphic Therapeutic, Inc.

  公开号：US20200071322A1

  公开（公告）日：2020-03-05

  Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.