N-benzyl-N,2-dimethylbenzamide | 13493-23-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-benzyl-N,2-dimethylbenzamide
• 英文别名: N-Benzyl-N,2-methyl-benzamid
• CAS: 13493-23-7
• 化学式: C₁₆H₁₇NO
• 分子量: 239.317
• InChiKey: WWGMRQYIAABIDX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-甲基苄胺 在 N-氯代丁二酰亚胺 、 硫酸氧钒水合物 作用下， 以 二氯甲烷 、 乙酸乙酯 为溶剂， 反应 50.0h， 生成 N-benzyl-N,2-dimethylbenzamide
  参考文献：
  名称：

  Oxidovanadium(IV) sulfate catalyses light-driven C–N bond formation

  摘要：

  DOI：

  10.1016/j.mcat.2023.113054

文献信息

• Visible-light-induced dehydrogenative amidation of aldehydes enabled by iron salts
  作者：Han Gao、Lin Guo、Yining Zhu、Chao Yang、Wujiong Xia

  DOI：10.1039/d2cc06507j

  日期：——

  A direct dehydrogenative amidation reaction of aldehydes and amines under a visible light mediated ligand-to-metal charge transfer (LMCT) process was described. In this protocol, aldehyde substrates were activated by photoinduced hydrogen atom abstraction (HAA), generating acyl chloride intermediates followed by nucleophilic addition of amines. The synthetic method furnishes good functional group tolerance

  描述了在可见光介导的配体到金属电荷转移 (LMCT) 过程中醛和胺的直接脱氢酰胺化反应。在该协议中，醛底物被光诱导氢原子提取 (HAA) 激活，生成酰氯中间体，然后亲核加成胺。该合成方法对脂肪族和芳香族组分均具有良好的官能团耐受性和广泛的底物范围。
• AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF
  申请人：Astellas Pharma Inc.

  公开号：EP2206707B1

  公开（公告）日：2014-07-23
• FORMULATIONS
  申请人：Bell Gordon Alistair

  公开号：US20120184438A1

  公开（公告）日：2012-07-19

  This invention relates to agrochemical compositions comprising a benzamide compound of formula (I) where R 1 is fluoro, methoxy or C 1-4 alkyl; R 2 and R 3 are each independently optionally substituted C 1-6 alkyl or optionally substituted C 2-6 alkenyl; or R 3 is hydrogen and R 3 is optionally substituted C 5-8 alkyl or optionally substituted C 4-6 alkenyl or optionally substituted benzyl; or R 2 and R 3 and the nitrogen atom to which they are both attached together form an optionally substituted 5-, 6- or 7-membered ring, which ring optionally contains at least one further heteroatom selected from O, N and S; to the use of those benzamide compounds as solvents; to certain novel compounds of formula (I); and to a process for preparing those novel compounds.
• US8304547B2
  申请人：——

  公开号：US8304547B2

  公开（公告）日：2012-11-06
• [EN] FORMULATIONS<br/>[FR] FORMULATIONS
  申请人：SYNGENTA LTD

  公开号：WO2011010082A2

  公开（公告）日：2011-01-27

  This invention relates to agrochemical compositions comprising a benzamide compound of formula (I) where R1 is fluoro, methoxy or C1-4 alkyl; R2 and R3 are each independently optionally substituted C1-6 alkyl or optionally substituted C2-6 alkenyl; or R3 is hydrogen and R3 is optionally substituted C5-8 alkyl or optionally substituted C4-6 alkenyl or optionally substituted benzyl; or R2 and R3 and the nitrogen atom to which they are both attached together form an optionally substituted 5-, 6- or 7-membered ring, which ring optionally contains at least one further heteroatom selected from O, N and S; to the use of those benzamide compounds as solvents; to certain novel compounds of formula (I); and to a process for preparing those novel compounds.