(5E)-5-(biphenyl-4-ylmethylidene)imidazolidine-2,4-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (5E)-5-(biphenyl-4-ylmethylidene)imidazolidine-2,4-dione
• 英文别名: (5E)-5-[(4-phenylphenyl)methylidene]imidazolidine-2,4-dione
• 化学式: C₁₆H₁₂N₂O₂
• 分子量: 264.28
• InChiKey: QIYDZMXXQWNWHJ-GXDHUFHOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Process for producing 4-biphenylylacetic acid
  申请人：LEDERLE (JAPAN) LTD.

  公开号：EP0212617B1

  公开（公告）日：1989-01-11
• Method For Production of Optically Active Biphenylalanine Compound or Salt or Ester Thereof
  申请人：Sugi Kiyoshi

  公开号：US20090011475A1

  公开（公告）日：2009-01-08

  Disclosed is a method for production of an optically active biphenylalanine compound represented by the formula (2): (wherein, R 2 is a protective group of an amino group, and R 3 and R 4 are each independently a hydrogen atom, etc.) or a salt thereof and an optically active biphenylalanine ester compound represented by the formula (3): (wherein, R 1 is an alkyl group, etc.) wherein the method comprises hydrolyzing a biphenylalanine ester compound represented by the formula (1): with a protease produced by a microorganism belonging to Bacillus sp. in the presence of at least one alkali selected from an alkali metal hydroxide and an alkaline earth metal hydroxide.
• US8017378B2
  申请人：——

  公开号：US8017378B2

  公开（公告）日：2011-09-13