N-(4-methylbenzyl)-2-pyrazinecarboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: N-(4-methylbenzyl)-2-pyrazinecarboxamide
• 英文别名: N-[(4-methylphenyl)methyl]pyrazine-2-carboxamide
• 化学式: C₁₃H₁₃N₃O
• 分子量: 227.26
• InChiKey: NVVMZNMAMDVIFQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  54.9
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] IMAGING TUBERCULOSIS WITH PYRAZINAMIDE CONTRAST AGENTS<br/>[FR] IMAGERIE DE LA TUBERCULOSE AU MOYEN D'AGENTS DE CONTRASTE DE TYPE PYRAZINAMIDE
  申请人：GE HEALTHCARE LTD

  公开号：WO2012022812A1

  公开（公告）日：2012-02-23

  The present invention provides novel in vivo imaging agents useful for detecting the presence of mycobacteria using in vivo imaging methods. Also provided by the present invention is a precursor compound useful in the synthesis of the in vivo imaging agents of the invention, and a method to obtain the in vivo imaging agent of the invention using said precursor compound. Methods of in vivo imaging and diagnosis in which the in vivo imaging agent of the invention finds use are also provided.