2,2'-((2-(dimethylamino)ethyl)azanedyl)bis(ethan-1-ol) | 3197-07-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2,2'-((2-(dimethylamino)ethyl)azanedyl)bis(ethan-1-ol)
• 英文别名: 2,2'-((2-(dimethylamino)ethyl)azanediyl)bis(ethan-1-ol)；2,2'-{[2-(Dimethylamino)ethyl]azanediyl}di(ethan-1-ol)；2-[2-(dimethylamino)ethyl-(2-hydroxyethyl)amino]ethanol
• CAS: 3197-07-7
• 化学式: C₈H₂₀N₂O₂
• mdl: MFCD16152302
• 分子量: 176.259
• InChiKey: KOTHTSHIGYKYDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.9
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2922199090

反应信息

• 作为反应物：
  描述：

  2,2'-((2-(dimethylamino)ethyl)azanedyl)bis(ethan-1-ol) 生成 1--2-dimethylamino-ethan
  参考文献：
  名称：

  Some Amino and Ammonio Nitrogen Mustard Analogs

  摘要：

  DOI：

  10.1021/jm00329a020
• 作为产物：
  描述：

  二甲氨基氯乙烷盐酸 、 二乙醇胺 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 以23 %的产率得到2,2'-((2-(dimethylamino)ethyl)azanedyl)bis(ethan-1-ol)
  参考文献：
  名称：

  Fe/Ti 协同作用实现 Fe 催化的钛酸芳基酯双官能化

  摘要：

  已经开发了通过双 C-H 活化的 Fe 催化的钛酸芳基酯双官能化，其中钛酸芳基酯通过邻位C-H 活化被芳基化，然后是C-Ti 键的ipso亲电捕获。邻位C-H 芳基化应由 1,2-Fe/Ti 协同异双金属亚芳基中间体促进，并代表由易于转化的 C-Ti 基团引导的邻位C-H 铁化。常见的苯甲酰胺、酯类和腈类用作芳基化试剂，这涉及由这些官能团引导的另一种邻位C-H 活化。

  DOI：

  10.1021/acs.orglett.3c00975

文献信息

• CATALYST COMPOSITION FOR PRODUCTION OF POLYURETHANE RESIN AND METHOD FOR PRODUCING POLYURETHANE RESIN (AS AMENDED)
  申请人：Kometani Hiroyuki

  公开号：US20100130629A1

  公开（公告）日：2010-05-27

  Disclosed is a catalyst composition for polyurethane resin production which contains (A) triethylenediamine, (B) a specific polyisocyanurating catalyst and/or (C) a specific highly temperature-sensitive catalyst. By using this catalyst composition, a polyurethane resin can be molded with good curability, while suppressing initial reactivity. Consequently, a polyurethane resin having excellent moldability and fluidity can be produced with high productivity by using the catalyst composition. The thus-obtained polyurethane resin is suitably applicable to shoe soles. The component (B) is selected from the group consisting of alkali metal salts of carboxylic acids, quaternary ammonium compounds expressed as R 1 R 2 R 3 R 4 N + ,X − , N,N,N′-trimethylaminoethylethanolamine, and 2,4,6-tris(dimethylaminomethyl)phenol, while the component (C) is selected from the group consisting of triazole salts and benzotriazole salts of 1,8-diazabicyclo[5.4.0]undecene-7 or 1,5-diazabicyclo[4.3.0]nonene-5. The mixing ratio of the component (B) and/or the component (C) to the component (A) is from 2% by weight to 60% by weight.

  本发明涉及一种用于聚氨酯树脂生产的催化剂组合物，其包含（A）三乙二胺，（B）特定的聚异氰酸酯催化剂和/或（C）特定的高温敏感催化剂。通过使用这种催化剂组合物，可以制造具有良好可固化性的聚氨酯树脂，同时抑制初始反应性。因此，使用催化剂组合物可以生产具有出色的可塑性和流动性的聚氨酯树脂，并具有高生产率。因此制造的聚氨酯树脂适用于鞋底。组分（B）选自羧酸的碱金属盐、表示为R1R2R3R4N+，X−的季铵化合物、N，N，N′-三甲基氨基乙基乙醇胺和2,4,6-三（二甲胺甲基）苯酚组成的群，而组分（C）选自1,8-二氮杂双环[5.4.0]十一烯-7或1,5-二氮杂双环[4.3.0]壬烯-5的三唑盐和苯并三唑盐组成的群。组分（B）和/或组分（C）与组分（A）的混合比重为2重量％至60重量％。
• Synergism of Fe/Ti Enabled Regioselective Arene Difunctionalization
  作者：Yi-Ming Wei、Xiao-Di Ma、Meng-Fei Wang、Xin-Fang Duan

  DOI：10.1021/jacs.2c13207

  日期：2023.1.25

  Regioselective difunctionalization of arenes remains a long-standing challenge in organic chemistry. We report a novel and general Fe/Ti synergistic methodology for regioselective synthesis of various polysubstituted arenes through either E/E′ or Nu/E ortho difunctionalizations of arenes. Preliminary results showed that an unprecedented 1,2-Fe/Ti heterobimetallic arylene intermediate bearing two distinct

  芳烃的区域选择性双官能化仍然是有机化学中长期存在的挑战。我们报告了一种新颖且通用的 Fe/Ti 协同方法，用于通过芳烃的 E/E' 或 Nu/E邻位双官能化区域选择性合成各种多取代芳烃。初步结果表明，具有两个不同 C-M 键的前所未有的 1,2-Fe/Ti 杂双金属亚芳基中间体对于区域选择性双官能化至关重要。
• Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin
  申请人：Tosoh Corporation

  公开号：EP1092737A2

  公开（公告）日：2001-04-18

  A catalyst composition for the production of a polyurethane resin, which comprises an amine compound of the following formula (1): wherein each of R1 and R2 which are independent of each other, is a C1-4 alkyl group, such alkyl groups bonded to each other directly or via a nitrogen atom or an oxygen atom to form a ring structure, a dimethylaminopropyl group or a diethylaminopropyl group, and R3 is a C2-16 straight chain or branched chain alkylene group, and an amine compound of the following formula (2): wherein each of R4 and R5 which are independent of each other, is a C1-4 alkyl group, such alkyl groups bonded to each other directly or via a nitrogen atom or an oxygen atom to form a ring structure, a dimethylaminopropyl group or a diethylaminopropyl group, R6 is a C2-16 straight chain or branched chain alkylene group, R7 is a C2-3 straight chain or branched chain alkylene group, and n is an integer of from 0 to 2.

  一种用于生产聚氨酯树脂的催化剂组合物，它包括下式(1)的胺化合物： 其中相互独立的 R1 和 R2 均为 C1-4 烷基，此类烷基直接或通过氮原子或氧原子相互键合以形成环状结构、二甲基氨基丙基或二乙基氨基丙基，R3 为 C2-16 直链或支链亚烷基，以及下式（2）的胺化合物： R4 和 R5 均为 C1-4 烷基，此类烷基直接或通过氮原子或氧原子相互键合以形成环状结构、二甲基氨基丙基或二乙基氨基丙基，R3 为 C2-16 直链或支链亚烷基： 其中相互独立的 R4 和 R5 各为 C1-4 烷基，此类烷基直接或通过氮原子或氧原子相互键合以形成环状结构、二甲基氨基丙基或二乙基氨基丙基，R6 为 C2-16 直链或支链亚烷基，R7 为 C2-3 直链或支链亚烷基，n 为 0 至 2 的整数。
• Process for the production of flexible polyurethane foams
  申请人：Tosoh Corporation

  公开号：EP1312630A1

  公开（公告）日：2003-05-21

  Flexible polyurethane foams are produced by reacting a polyol and a polyisocyanate in the presence of a catalysts and other auxiliary agents, the process characterized in that a tin-based catalyst is not used. One process includes reacting a polyether polyol containing at least 5% by weight of an oxyethylene group in the chain and having a terminal secondary OH group, a toluene diisocyanate and/or a derivative, and one or more specified imidazole compounds, the process conducted in the absence of a tin-based catalyst.

  柔性聚氨酯泡沫塑料是通过多元醇和多异氰酸酯在催化剂和其他辅助剂的存在下发生反应而生产的，该工艺的特点是不使用锡基催化剂。一种工艺包括使一种在链中含有至少 5%（按重量计）氧乙烯基并具有末端仲羟基的聚醚多元醇、一种甲苯二异氰酸酯和/或衍生物以及一种或多种特定咪唑化合物发生反应，该工艺在无锡基催化剂的情况下进行。
• HYDROXYALKYLATED POLYALKYLENEPOLYAMINE COMPOSITION, METHOD FOR PRODUCING SAME AND METHOD FOR PRODUCING POLYURETHANE RESIN USING SUCH HYDROXYALKYLATED POLYALKYLENEPOLYAMINE COMPOSITION
  申请人：TOSOH CORPORATION

  公开号：EP1813599A1

  公开（公告）日：2007-08-01

  Disclosed is a novel hydroxyalkylated polyalkylene polyamine composition, and a method for preparing the hydroxyalkylated polyalkylene polyamine composition at low cost. Further disclosed is a method for producing a polyurethane resin by using the hydroxyalkylated polyalkylene polyamine composition containing at least two hydroxyalkylated polyalkylene polyamines represented by the following general formula (1): In the formula (1), R1 to R5 are independently a C1 to C3 alkyl group or a substituent represented by the following general formula (2): wherein R6 and R7 are independently a hydrogen atom or a C1 to C4 alkyl group, and p is an integer from 1 to 3; and R5 and R1, R2, R3, or R4 may arbitrarily bond together to form a ring; at least one of R1 to R5 is a substituent represented by the general formula (2) but all of R1 to R5 cannot be substituents represented by the general formula (2) at the same time; n and m are independently an integer from 1 to 5; and a is an integer from 1 to 6.

  本发明公开了一种新型羟烷基化聚亚烷基多胺组合物，以及一种低成本制备羟烷基化聚亚烷基多胺组合物的方法。还公开了一种使用羟烷基化聚亚烷基多胺组合物生产聚氨酯树脂的方法，该组合物至少含有两种由以下通式（1）表示的羟烷基化聚亚烷基多胺： 在式(1)中，R1 至 R5 独立地为 C1 至 C3 烷基或由下式(2)代表的取代基： 其中 R6 和 R7 独立地为氢原子或 C1 至 C4 烷基，p 为 1 至 3 的整数；R5 和 R1、R2、R3 或 R4 可任意地键合在一起形成环；R1 至 R5 中至少有一个是通式（2）所代表的取代基，但 R1 至 R5 不能全部同时为通式（2）所代表的取代基；n 和 m 独立地为 1 至 5 的整数；a 为 1 至 6 的整数。