N-cyclopentyl-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: N-cyclopentyl-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
• 化学式: C₁₉H₁₇F₃N₄O
• 分子量: 374.4
• InChiKey: UPNJWFJYPJEEJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  59.3
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases
  申请人：Chunduru K. Srinivas

  公开号：US20070269420A1

  公开（公告）日：2007-11-22

  The present invention is directed to compounds, compositions and methods for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus. Also within the scope of this invention are assay methods for identifying agents that modulate NS4B activity, as well as kits for performing such methods.