N-[4-(1H-benzimidazol-2-yl)phenyl]benzofuran-2-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: N-[4-(1H-benzimidazol-2-yl)phenyl]benzofuran-2-carboxamide
• 英文别名: N-[4-(1H-benzimidazol-2-yl)phenyl]-1-benzofuran-2-carboxamide
• 化学式: C₂₂H₁₅N₃O₂
• 分子量: 353.4
• InChiKey: GDEGWMCLQDGQFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  70.9
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• CANCER DIAGNOSTIC AND THERAPEUTIC METHOD TARGETING MOLECULES EXPRESSED IN CANCER STEM CELLS
  申请人：NIIGATA UNIVERSITY

  公开号：US20150297694A1

  公开（公告）日：2015-10-22

  The present invention provides a novel method for determining cancer malignancy, a novel cancer diagnostic method, a novel method for determining prognosis, a novel vaccine for cancer treatment, and a novel vaccine for suppressing cancer metastasis. Specifically, the invention provides a cancer malignancy evaluation method that comprises the step of measuring a DDX3X expression level in a cancer tissue, and the step of evaluating malignancy of the cancer tissue by using the DDX3X expression level.
• [EN] CANCER DIAGNOSTIC AND THERAPEUTIC METHOD TARGETING MOLECULES EXPRESSED IN CANCER STEM CELLS<br/>[FR] MÉTHODE DE DIAGNOSTIC ET THÉRAPEUTIQUE DU CANCER CIBLANT DES MOLÉCULES EXPRIMÉES DANS DES CELLULES SOUCHES CANCÉREUSES
  申请人：UNIV NIIGATA

  公开号：WO2014038682A2

  公开（公告）日：2014-03-13

  The present invention provides a novel method for determining cancer malignancy, a novel cancer diagnostic method, a novel method for determining prognosis, a novel vaccine for cancer treatment, and a novel vaccine for suppressing cancer metastasis. Specifically, the invention provides a cancer malignancy evaluation method that comprises the step of measuring a DDX3X expression level in a cancer tissue, and the step of evaluating malignancy of the cancer tissue by using the DDX3X expression level.