N-phenylbenzo[b]thiophene-2-carboxamide 1,1-dioxide | 149327-48-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-phenylbenzo[b]thiophene-2-carboxamide 1,1-dioxide
• 英文别名: benzothiophene-2-carboxanilide S,S-dioxide；1,1-dioxo-N-phenyl-1-benzothiophene-2-carboxamide
• CAS: 149327-48-0
• 化学式: C₁₅H₁₁NO₃S
• 分子量: 285.323
• InChiKey: GLMCUBOUUIBLPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  71.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-phenylbenzo[b]thiophene-2-carboxamide 在 二甲基二环氧乙烷 作用下， 以 二氯甲烷 、 丙酮 为溶剂， 反应 0.17h， 以98%的产率得到N-phenylbenzo[b]thiophene-2-carboxamide 1,1-dioxide
  参考文献：
  名称：

  用H2O2和P2O5水溶液将贫电子的苯并[b]噻吩轻松氧化为相应的砜。

  摘要：

  描述了一种使用H（2）O（2）和P（2）O（5）的水溶液轻松氧化苯并[b]噻吩向其相应的砜的清晰转化的方法。该溶液可以制备并以多克的规模存储，保质期可达两周。

  DOI：

  10.1039/b924333j

文献信息

• Benzothiophene-2-carboxamide S,S-dioxides and use
  申请人：Bayer Aktiengesellschaft

  公开号：US05244893A1

  公开（公告）日：1993-09-14

  New compounds of the formula (I) ##STR1## in which R.sup.1 -R.sup.6 have the meanings given in the description, their preparation and use in plant protection, the protection of materials and in the field of human and veterinary medicine. Formula (I) gives a definition of the compounds which can be prepared by analogous processes, for example from suitable benzothiophene derivatives by oxidation.

  公式（I）的新化合物如下：##STR1## 其中R.sup.1-R.sup.6在说明中给出了它们的含义，它们的制备和用途包括植物保护、材料保护以及人类和兽医学领域。公式（I）定义了可以通过类似的过程制备的化合物，例如通过氧化适当的苯并噻吩衍生物。
• ANTI-ALLERGEN COMBINATIONS OF CALCIUM AND LANTHANUM SALTS
  申请人：Janssen Pharmaceutica, N.V.

  公开号：EP2323485B1

  公开（公告）日：2013-10-16
• Imazalil compositions comprising alkoxylated amines
  申请人：Bylemans Dany Leopold Jozefien

  公开号：US20090093505A1

  公开（公告）日：2009-04-09

  The present invention relates to the use of alkoxylated amines to enhance the activity of fungicidal formulations comprising the fungicidal compound imazalil. It also relates to formulations comprising imazalil and alkoxylated amines. These formulations are useful to protect materials, plants, fruits or seeds against fungi.
• ANTI-ALLERGEN COMBINATIONS OF CALCIUM AND LANTHANUM
  申请人：Bylemans Dany Leopold Jozefien

  公开号：US20110135750A1

  公开（公告）日：2011-06-09

  The present invention relates to certain combinations of alkaline earth metal salts and rare earth metal salts which provide an improved denaturing effect on allergens. More particularly, the present invention relates to compositions comprising a combination of calcium salts and lanthanum salts in respective proportions to produce a synergistic denaturing effect on allergens. Compositions comprising these combinations are particularly effective for use in an ex vivo method for denaturing allergens associated with house dust mites and other common allergens such as cat dander, molds, cockroach, pollen and the like.
• IMAZALIL COMPOSITIONS COMPRISING ALKOXYLATED AMINES
  申请人：Bylemans Dany Leopold Jozefien

  公开号：US20110196006A1

  公开（公告）日：2011-08-11

  The present invention relates to the use of alkoxylated amines to enhance the activity of fungicidal formulations comprising the fungicidal compound imazalil. It also relates to formulations comprising imazalil and alkoxylated amines. These formulations are useful to protect materials, plants, fruits or seeds against fungi.