fluoro N,N-diphenylcarbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: fluoro N,N-diphenylcarbamate
• 化学式: C₁₃H₁₀FNO₂
• 分子量: 231.22
• InChiKey: GYLYCMOLTQSLRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• CARBAMATE COMPOUNDS AND METHODS OF USE IN DISEASES OF THE NERVOUS SYSTEM
  申请人：Treventis Corporation

  公开号：US20150217004A1

  公开（公告）日：2015-08-06

  In general, among other things, compounds of Formula I are provided: or a pharmaceutically acceptable salt thereof, in which R 1-7, 9-10 are each independently selected from the group consisting of hydrogen, hydroxy, alkoxy, and alkyl; and R 8 is selected from the group consisting of fluoro, iodo, and tributyltin. Other compounds are also provided. Methods of treatment and diagnosis are also provided.

  一般而言，本发明提供了公式I的化合物：或其药学上可接受的盐，其中R1-7、9-10各自独立地选自氢、羟基、烷氧基和烷基的群组，而R8选自氟、碘和三丁基锡的群组。本发明还提供了其他化合物。本发明还提供了治疗和诊断方法。
• [EN] CARBAMATE COMPOUNDS AND METHODS OF USE IN DISEASES OF THE NERVOUS SYSTEM<br/>[FR] COMPOSÉS CARBAMATE ET PROCÉDÉS DESTINÉS À ÊTRE UTILISÉS DANS LES MALADIES DU SYSTÈME NERVEUX
  申请人：TREVENTIS CORP

  公开号：WO2014039526A2

  公开（公告）日：2014-03-13

  In general, among other things, compounds of Formula I are provided: or a pharmaceutically acceptable salt thereof, in which R1-7 9-10 are each independently selected from the group consisting of hydrogen, hydroxy, alkoxy, and alkyl; and R8 is selected from the group consisting of fluoro, iodo, and tributyltin. Other compounds are also provided. Methods of treatment and diagnosis are also provided.