2-(dimethylamino)ethyl (E)-3-(2-hydroxyethoxy)-2-methylprop-2-enoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 乙烯酯类
• 英文名称: 2-(dimethylamino)ethyl (E)-3-(2-hydroxyethoxy)-2-methylprop-2-enoate
• 化学式: C₁₀H₁₉NO₄
• 分子量: 217.26
• InChiKey: WBBTWAXYLGKBID-CMDGGOBGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  59
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Compositions and methods for the delivery of therapeutics
  申请人：Board of Regents of the University of Nebraska

  公开号：US11311545B2

  公开（公告）日：2022-04-26

  The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.

  本发明提供了将抗病毒药物传递到细胞或对象的组合物和方法。
• Analyte sensing for eye injuries and conditions
  申请人：The Board of Trustees of the University of Illinois

  公开号：US10400262B2

  公开（公告）日：2019-09-03

  A biosensor for the detection of an analyte such as ascorbic acid is provided. Also provided is a device comprising the biosensor. In addition, methods of detecting analytes such as ascorbic acid in a sample, and methods of a point-of-care diagnosis of eye disease and eye injury are provided.

  提供了一种用于检测抗坏血酸等分析物的生物传感器。还提供了一种包含该生物传感器的装置。此外，还提供了检测样品中抗坏血酸等分析物的方法，以及眼病和眼损伤的护理点诊断方法。
• COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTICS
  申请人：Board of Regents of the University of Nebraska

  公开号：EP3110422A1

  公开（公告）日：2017-01-04
• TUNABLE MULTIMODAL NANOPARTICLES AND METHODS OF USE THEREOF
  申请人：Board of Regents of the University of Nebraska

  公开号：US20150079007A1

  公开（公告）日：2015-03-19

  Tunable nanoparticles and methods of use thereof are provided. In accordance with the instant invention, tunable nanoparticles comprising a metal nanoparticle core (e.g., a paramagnetic particle (e.g., USPIO) or a quantum dot) and a polymer linked to a metal binding moiety are provided. The polymer of the nanoparticle is bound to the metal nanoparticle core by the metal binding moiety and coats the metal nanoparticle core. In a particular embodiment, the metal binding moiety comprises bisphosphonate, pyrophosphate, or a derivative thereof. In a particular embodiment, the polymer is a hydrophilic polymer, an amphiphilic block copolymer or an ionic block copolymer.
• SMALL MAGNETITE THERAPEUTICS AND METHODS OF USE THEREOF
  申请人：BOARD OF THE REGENTS OF THE UNIVERSITY OF NEBRASKA

  公开号：US20150125401A1

  公开（公告）日：2015-05-07

  The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.