6-(ethynylamino)-1H-pyrimidin-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 6-(ethynylamino)-1H-pyrimidin-2-one
• 化学式: C₆H₅N₃O
• 分子量: 135.12
• InChiKey: FTQHFRXEVNGQIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  53.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• RESTRICTION ENDONUCLEASES AND THEIR USE
  申请人：Thermo Fisher Scientific Baltics UAB

  公开号：EP2870240A2

  公开（公告）日：2015-05-13
• COLORIMETRIC LABELING AND DETECTION METHODS AND COMPOSITIONS
  申请人：Life Technologies Corporation

  公开号：EP3344782A1

  公开（公告）日：2018-07-11
• METHODS AND SYSTEMS FOR GUIDE RNA DESIGN AND USE
  申请人：Synthego Corporation

  公开号：EP3794130A1

  公开（公告）日：2021-03-24
• COMPOSITIONS AND METHODS FOR ENGRAFTMENT OF BASE EDITED CELLS
  申请人：Beam Therapeutics Inc.

  公开号：EP4103704A1

  公开（公告）日：2022-12-21
• Colorimetric Labeling and Detection Methods and Compositions
  申请人：LIFE TECHNOLOGIES CORPORATION

  公开号：US20190154696A1

  公开（公告）日：2019-05-23

  The present disclosure provides methods, compositions and kits for measuring cellular nascent nucleic acid synthesis by colorimetric labeling of nucleic acid. The nucleic acid synthesis can be measured as cell proliferation, DNA or RNA synthesis, gene expression or apoptosis. Additionally, these methods may be used to screen compounds for their effect on cellular proliferation by treating cells or an organism with the test compound simultaneous to or before treatment with a competitive nucleoside analog.