[2-(4-Methylbenzoyl)hydrazinyl] 2-phenylacetate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-(4-Methylbenzoyl)hydrazinyl] 2-phenylacetate
• 英文别名: [2-(4-methylbenzoyl)hydrazinyl] 2-phenylacetate
• 化学式: C₁₆H₁₆N₂O₃
• 分子量: 284.31
• InChiKey: RLGZJHXCSKLTOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  67.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS
  申请人：Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

  公开号：EP2852387A2

  公开（公告）日：2015-04-01
• [EN] SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS<br/>[FR] INHIBITEURS SÉLECTIFS DE CELLULES INDIFFÉRENCIÉES
  申请人：YISSUM RES DEV CO

  公开号：WO2013175474A2

  公开（公告）日：2013-11-28

  Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.