4-(5,6-dioxo-1,2-dihydropyridazin-3-yl)benzonitrile;4-(5-methoxy-6-oxo-1H-pyridazin-3-yl)benzonitrile

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 4-(5,6-dioxo-1,2-dihydropyridazin-3-yl)benzonitrile;4-(5-methoxy-6-oxo-1H-pyridazin-3-yl)benzonitrile
• 化学式: C23H16N6O4
• 分子量: 440.4
• InChiKey: SBEATCZKDGRWRA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.92
• 重原子数：
  33
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  157
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• [EN] THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES<br/>[FR] HYDROXYPYRIDONES, HYDROXYPYRIMIDINONES ET HYDROXYPYRIDAZINONES THÉRAPEUTIQUES
  申请人：UNIV RUTGERS

  公开号：WO2014043252A2

  公开（公告）日：2014-03-20

  The invention provides compounds of formula (I): and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.