N-(2-chloro-4-methylphenyl)-2-[1-(1,1-dimethylpiperidin-1-ium-4-yl)benzimidazol-2-yl]sulfanylpropanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: N-(2-chloro-4-methylphenyl)-2-[1-(1,1-dimethylpiperidin-1-ium-4-yl)benzimidazol-2-yl]sulfanylpropanamide
• 化学式: C24H30ClN4OS+
• 分子量: 458.0
• InChiKey: SVVHSGOBZGBUQH-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  72.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• IMIDAZOLYL AMIDE COMPOUNDS AND USES RELATED THERETO
  申请人：Plemper Richard K.

  公开号：US20140080828A1

  公开（公告）日：2014-03-20

  This disclosure relates to antiviral compounds disclosed herein and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising 2-((benzo[d]imidazol-2-yl)thio)-N-phenylpropanamide derivatives, N-phenyl-2-((1-phenyl-benzo[d]imidazol-2-yl)thio)propanamide derivatives, or 2-((benzo[d]imidazol-2-yl)thio)-N-(2-chloro-4-methylphenyl)propanamide derivatives. The derivatives may be substituted with one or more substituents. Typically, the pharmaceutical composition comprises a compound of Formula (I), or salt, prodrug, or ester thereof wherein X, Y, and R1 to R7 are described herein.
• US9365523B2
  申请人：——

  公开号：US9365523B2

  公开（公告）日：2016-06-14