[3-Carbamoyloxy-2-[4-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethylamino]-4-oxobutoxy]propyl] carbamate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: [3-Carbamoyloxy-2-[4-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethylamino]-4-oxobutoxy]propyl] carbamate
• 英文别名: [3-carbamoyloxy-2-[4-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethylamino]-4-oxobutoxy]propyl] carbamate
• 化学式: C₁₈H₂₇N₅O₉
• 分子量: 457.4
• InChiKey: IHUIBNGISYSCSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  32
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  209
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• Water-Soluble Polymer-Linked Binding Moiety and Drug Compounds
  申请人：Riggs-Sauthier Jennifer

  公开号：US20140088021A1

  公开（公告）日：2014-03-27

  Compounds comprising a binding moiety, water-soluble, non-peptidic polymer, and drug are provided. Also provided are methods preparing such compounds, compositions comprising such compounds and methods for administering and using such compounds and compositions.
• POLYMER DERIVATIVES HAVING PARTICULAR ATOM ARRANGEMENTS
  申请人：Nektar Therapeutics

  公开号：US20200246471A1

  公开（公告）日：2020-08-06

  Polymeric reagents are provided comprising a moiety of atoms arranged in a specific order, wherein the moiety is positioned between a water-soluble polymer and a reactive group. The polymeric reagents are useful for, among other things, forming polymer-active agent conjugates. Related methods, compositions, preparations, and so forth are also provided.
• US9913913B2
  申请人：——

  公开号：US9913913B2

  公开（公告）日：2018-03-13