7-methoxy-3-(phenylsulfonyl)-2H-chromen-2-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 7-methoxy-3-(phenylsulfonyl)-2H-chromen-2-one
• 英文别名: 3-(benzenesulfonyl)-7-methoxychromen-2-one
• 化学式: C₁₆H₁₂O₅S
• 分子量: 316.3
• InChiKey: BBWRKQBHONFQPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  78
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Sensitized photopolymerizable compositions and use thereof in lithographic printing plates
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0730201A1

  公开（公告）日：1996-09-04

  Improved photopolymerization initiator systems are comprised of a spectral sensitizer that sensitizes in the ultraviolet or visible regions of the spectrum and an N-aryl, O-aryl or S-aryl polycarboxylic acid co-initiator. The improved initiator systems are incorporated in photo-polymerizable compositions containing one or more addition-polymerizable ethylenically-unsaturated compounds to form compositions suitable for the preparation of radiation-sensitive layers in lithographic printing plates adapted to be imagewise-exposed with ultraviolet- or visible-light-emitting lasers such as argon-ion lasers and frequency doubled Nd:YAG lasers. Such plates are able to effectively meet the dual requirements of very high photospeed and very good shelf-life required in computer-to-plate systems.

  改进的光聚合引发剂体系由在光谱的紫外线或可见光区域敏化的光谱敏化剂和 N-芳基、O-芳基或 S-芳基聚羧酸共引发剂组成。改进后的引发剂体系与含有一种或多种可加成聚合的乙烯基不饱和化合物的光聚合组合物结合，形成的组合物适用于制备平版印刷板中的辐射敏感层，该板可使用紫外线或可见光发射激光器（如氩离子激光器和倍频 Nd:YAG 激光器）进行图像曝光。这种印版能够有效地满足计算机直接制版系统对极高的光速和极好的保存期限的双重要求。
• Peel-developable lithographic printing plate
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0795790A2

  公开（公告）日：1997-09-17

  A peel-developable lithographic printing plate is comprised of a substrate, a hydrophilic layer comprising a polymeric acid overlying the substrate, a radiation-sensitive image-forming layer overlying the hydrophilic layer and a stripping layer that is strippably adhered to the image-forming layer. The image-forming layer is comprised of a photopolymerizable composition comprising a polymeric binder, a plurality of addition-polymerizable ethylenically-unsaturated compounds at least one of which possesses phosphorus-derived acidic functionality and a photopolymerization initiator. After imagewise exposure of the plate to activating radiation, the stripping layer is peeled from the image-forming layer with only the unexposed regions of the image-forming layer adhering thereto so as to reveal the underlying hydrophilic layer and thereby form a lithographic printing surface.

  一种可剥离显影平版印刷板由基底、覆盖在基底上的由聚合物酸组成的亲水层、覆盖在亲水层上的辐射敏感图像形成层和可剥离地粘附在图像形成层上的剥离层组成。图像形成层由可光聚合的组合物组成，该组合物包括聚合物粘合剂、多种可加成聚合的乙烯基不饱和化合物（其中至少一种具有磷衍生的酸性官能团）和光聚合引发剂。将印版按图像方向暴露在活化辐射下后，剥离层从图像形成层上剥离，只有图像形成层的未暴露区域附着其上，以显示底层亲水层，从而形成平版印刷表面。
• Small molecule agonists and antagonists of NR2F6 activity in animals
  申请人：Zander Therapeutics, Inc.

  公开号：US10472351B2

  公开（公告）日：2019-11-12

  The present technology is directed to modulators of nuclear receptor activity, specifically to the modulation of NR2F6 activity and NR2F6 utilizing compounds, and the immune modulation and modulation of cancer stem cell activity through administration of compounds described herein to animals.

  本技术针对核受体活性调节剂，特别是针对 NR2F6 活性调节和 NR2F6 利用化合物，以及通过对动物施用本文所述化合物进行免疫调节和癌症干细胞活性调节。
• Small molecule agonists and antagonists of NR2F6 activity
  申请人：ZANDER THERAPEUTICS, INC.

  公开号：US11377442B2

  公开（公告）日：2022-07-05

  The present technology is directed to modulators of nuclear receptor activity, specifically to the modulation of NR2F6 activity and NR2F6 utilizing compounds, and the immune modulation and modulation of cancer stem cell activity through administration of compounds described herein.

  本技术针对核受体活性调节剂，特别是针对 NR2F6 活性调节和 NR2F6 利用化合物，以及通过服用本文所述化合物进行免疫调节和癌症干细胞活性调节。
• Photopolymerization systems and their use
  申请人：——

  公开号：US20040198859A1

  公开（公告）日：2004-10-07

  Coinitiator systems for photopolymerization of photopolymerizable compounds containing olefinic unsaturation are described. Such systems comprise (A) either a combination of at least one coumarin photoinitiator and at least one coinitiator compound which is a hydrogen atom donating coinitiator or an electron donating coinitiator, or at least one coumarin photoinitiator having in its molecular structure at least one photosensitizing amino group; and (B) at least one compound containing at least one maleimide or maleic anhydride derivative. Photopolymerizable compositions which comprise, in addition to such a coinitiator system, at least one photopolymerizable compound containing olefinic unsaturation are also described.

  描述了用于含烯烃不饱和的可光聚合化合物的光聚合的共引发剂体系。这种体系包括：(A) 至少一种香豆素光引发剂和至少一种辅引发剂化合物的组合，后者是一种氢原子捐赠型辅引发剂或电子捐赠型辅引发剂，或者至少一种香豆素光引发剂在其分子结构中具有至少一个光敏氨基；(B) 至少一种含有至少一种马来酰亚胺或马来酸酐衍生物的化合物。除上述共引发剂体系外，还描述了至少一种含有烯烃不饱和的可光聚合化合物的可光聚合组合物。