4-(Hydroxymethyl)-7-(1-hydroxypropoxy)chromen-2-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 4-(Hydroxymethyl)-7-(1-hydroxypropoxy)chromen-2-one
• 英文别名: 4-(hydroxymethyl)-7-(1-hydroxypropoxy)chromen-2-one
• 化学式: C₁₃H₁₄O₅
• 分子量: 250.25
• InChiKey: BLKHUSREOYFPTQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• BIO-INSPIRED AND ANTIMICROBIAL POLYMERS CONTAINING AMINO ACID-LIKE MONOMER BUILDING BLOCKS
  申请人：Joy Abraham

  公开号：US20170172147A1

  公开（公告）日：2017-06-22

  Methods for killing a microbial are provided that include introducing a functionalized amide polymer to a microbe, where the functionalized amide polymer includes a polymer backbone selected from polyesters and polyurethanes; an amide group with a pendant functional group, where the nitrogen atom of the amide group is part of the polymer backbone; and a net positive charge.

  提供了一种杀灭微生物的方法，包括向微生物引入一个功能化酰胺聚合物，其中该功能化酰胺聚合物包括从聚酯和聚氨酯中选择的聚合物骨架；一个带有挂链功能基团的酰胺基团，其中酰胺基团的氮原子是聚合物骨架的一部分；以及净正电荷。
• [EN] PHOTORESPONSIVE COUMARIN BASED POLYMERS: SYNTHESIS AND APPLICATIONS<br/>[FR] POLYMÈRES PHOTOSENSIBLES À BASE DE COUMARINE : SYNTHÈSE ET APPLICATIONS
  申请人：UNIV AKRON

  公开号：WO2014074845A1

  公开（公告）日：2014-05-15

  A photoactive coumarin monomer includes a substituted coumarin molecule that has at least two functional groups may be used to produce a polymer with a coumarin unit or a coumarin derivative unit as part of the polymer backbone. The polymer with a coumarin unit or a coumarin derivative unit as part of the polymer backbone may be photoresponsive and/or bioabsorbable. Photoresponsive polymers with a coumarin unit or a coumarin derivative unit as part of the polymer backbone may crosslink when irradiated at a wavelength of about 320 nm to about 420 nm. The crosslink may be separated when the polymers are irradiated at a wavelength of about 230 nm to about 300. The polymers may also photocleave when irradiated with light at a wavelength of about 230 nm to about 300.

  一种光敏香豆素单体包括一个取代的香豆素分子，该分子具有至少两个功能基团，可用于制备具有香豆素单元或香豆素衍生单元作为聚合物骨架的聚合物。具有香豆素单元或香豆素衍生单元作为聚合物骨架的聚合物可能具有光响应性和/或生物可吸收性。具有香豆素单元或香豆素衍生单元作为聚合物骨架的光响应性聚合物可能在波长为约320 nm至约420 nm的辐射下交联。当聚合物在波长为约230 nm至约300 nm的辐射下时，交联可以分离。聚合物也可以在波长为约230 nm至约300 nm的光照下光解。
• PHOTORESPONSIVE COUMARIN BASED POLYMERS: SYNTHESIS AND APPLICATIONS
  申请人：The University of Akron

  公开号：EP2917196A1

  公开（公告）日：2015-09-16
• US9663614B2
  申请人：——

  公开号：US9663614B2

  公开（公告）日：2017-05-30