[2-methoxy-3-(propylaminomethoxy)propyl] N-propylcarbamate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: [2-methoxy-3-(propylaminomethoxy)propyl] N-propylcarbamate
• 化学式: C₁₂H₂₆N₂O₄
• 分子量: 262.35
• InChiKey: GJEXMKSCEQQOEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  18
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  68.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• POLYMER FACTOR IX MOIETY CONJUGATES
  申请人：Nektar Therapeutics

  公开号：US20140141483A1

  公开（公告）日：2014-05-22

  Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is polyethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
• Pharmaceutical Compositions of Conjugates Formed From Polymer Derivatives Having Particular Atom Arrangements
  申请人：Nektar Therapeutics

  公开号：US20140227218A1

  公开（公告）日：2014-08-14

  Pharmaceutical compositions of conjugates are provided. The conjugates can be prepared by (among other ways) conjugating a pharmacologically active agent with a polymeric reagent that has a particular arrangement of atoms. Related methods, preparations, and so forth are also provided.
• CONJUGATES OF AN ANTI-TNF-ALPHA ANTIBODY
  申请人：Nektar Therapeutics

  公开号：US20160030587A1

  公开（公告）日：2016-02-04

  Conjugates of an anti-TNF antibody and one or more nonpeptidic water soluble polymers are provided. Typically, the nonpeptidic water soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to a patient.
• US9044516B2
  申请人：——

  公开号：US9044516B2

  公开（公告）日：2015-06-02
• US9347054B2
  申请人：——

  公开号：US9347054B2

  公开（公告）日：2016-05-24