N-[(1-ethyltriazol-4-yl)methyl]-4-pyren-1-ylbutanamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: N-[(1-ethyltriazol-4-yl)methyl]-4-pyren-1-ylbutanamide
• 化学式: C₂₅H₂₄N₄O
• 分子量: 396.5
• InChiKey: BFNKUEHKQSDMMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  59.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NON COVALENT MOLECULAR STRUCTURE, COMPRISING A PYRENE BASED GLYCOCONJUGATE, DEVICE COMPRISING THE SAME AND ITS USE FOR DETECTION OF LECTIN
  申请人：Imberty Anne

  公开号：US20140147938A1

  公开（公告）日：2014-05-29

  The present invention relates to a non covalent molecular structure comprising a carbon nanostructure and a pyrene based glycoconjugate (I) which is linked to the said carbon nanostructure by a non covalent link, the said glycoconjugate (I) having the formula: wherein B is a group which is present on any of the ten carbon atoms of the pyrene structure represented in (I) susceptible to bear a substituent, and is represented by the following group: —(CH2) n -CO—NH-A, wherein n is an integer from 1 to 9, A is a group of formula: The present invention also relates to an electronic device comprising the said non covalent molecular structure, and to the use of this device for the detection of a lectin involved in bacterial or viral infections. Thus the invention also relates to a method for detecting the presence of a lectin in a sample to be analysed.

  本发明涉及一种非共价分子结构，包括碳纳米结构和与所述碳纳米结构通过非共价键连接的基于吡啶的糖共轭物(I)，所述糖共轭物(I)具有以下式：其中B是出现在(I)中所代表的吡啶结构的十个碳原子中的任意一个上，易于承载取代基，并由以下基团表示：—(CH2)n-CO—NH-A，其中n是1到9之间的整数，A是以下式的基团：本发明还涉及包括所述非共价分子结构的电子设备，以及利用该设备检测与细菌或病毒感染有关的凝集素的用途。因此，本发明还涉及一种检测样品中凝集素存在的方法。