2-(3-Chloro-5-methylphenyl)-4,6-diphenylpyrimidine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-(3-Chloro-5-methylphenyl)-4,6-diphenylpyrimidine
• 英文别名: 2-(3-chloro-5-methylphenyl)-4,6-diphenylpyrimidine
• 化学式: C₂₃H₁₇ClN₂
• 分子量: 356.8
• InChiKey: KBRPTHBBNDBRPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Novel Quinazoline Derivatives
  申请人：Zhang Qiang

  公开号：US20130035350A1

  公开（公告）日：2013-02-07

  This disclosure concerns novel quinazoline compounds of Formula (I) as defined in the specification and compositions comprising such novel compounds. These compounds are useful anticancer agents, especially in inhibiting the function of the EGF receptor tyrosine kinases, HER1 tyrosine kinase, and HER2 tyrosine kinase. Thus, the disclosure also concerns a method of treating hyperproliferative diseases or conditions, such as various cancers and benign prostate hyperplasia (BPH), by use of these novel compounds or a composition comprising such novel compounds.

  本公开涉及式（I）中定义的新型喹唑啉化合物及包含这些新型化合物的组合物。这些化合物是有用的抗癌剂，特别是在抑制EGF受体酪氨酸激酶、HER1酪氨酸激酶和HER2酪氨酸激酶的功能方面。因此，本公开还涉及使用这些新型化合物或包含这些新型化合物的组合物治疗过度增殖性疾病或病状，例如各种癌症和良性前列腺增生症（BPH）的方法。
• [EN] ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME<br/>[FR] COMPOSÉ ORGANIQUE ET DISPOSITIF ÉLECTROLUMINESCENT ORGANIQUE COMPRENANT UN TEL COMPOSÉ
  申请人：DOOSAN CORP

  公开号：WO2014081147A1

  公开（公告）日：2014-05-30

  본 발명은 정공 주입 및 수송능, 발광능 등이 우수한 신규 유기 화합물 및 상기 화합물을 하나 이상의 유기물층에 포함함으로써 발광효율, 구동 전압, 수명 등의 특성이 향상된 유기 전계 발광 소자에 관한 것이다.