[2-[(E)-2-[3,4-bis(hydroxymethyl)-5-methoxyphenyl]ethenyl]-4-[(E)-2-(3,5-dimethoxy-4-methylphenyl)ethenyl]-5-methoxyphenyl]methanol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: [2-[(E)-2-[3,4-bis(hydroxymethyl)-5-methoxyphenyl]ethenyl]-4-[(E)-2-(3,5-dimethoxy-4-methylphenyl)ethenyl]-5-methoxyphenyl]methanol
• 化学式: C₃₀H₃₄O₇
• 分子量: 506.6
• InChiKey: YPLJCQLGVPWBQV-CDJQDVQCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  37
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  97.6
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• METHOD OF TREATING CANCER USING A CURCUMIN DERIVATIVE
  申请人：DePuy Synthes Products, LLC

  公开号：US20140163116A1

  公开（公告）日：2014-06-12

  The present invention is directed to treating cancer with a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I).