7-Amino-4,6-dimethyl-3-(2-oxopropyl)chromen-2-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 7-Amino-4,6-dimethyl-3-(2-oxopropyl)chromen-2-one
• 英文别名: 7-amino-4,6-dimethyl-3-(2-oxopropyl)chromen-2-one
• 化学式: C₁₄H₁₅NO₃
• 分子量: 245.27
• InChiKey: IYNGELHFDYGLSX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  69.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• DETECTION AND REMOVAL OF CARIOUS DENTIN TISSUE
  申请人：Almhöjd Ulrica

  公开号：US20140161745A1

  公开（公告）日：2014-06-12

  The present invention relates to a kit of parts for detection and removal of carious dentin tissue comprising: (i) one or more compounds being a hydrazine derivative, and (ii) means for chemical treatment of carious dentin tissue. Further, the invention concerns a preparation containing an active, caries-dissolving two-component liquid in the form of a first active, caries-dissolving component and a second component which reduces the aggressiveness of the active component to mucous membranes, a viscosity increasing substance and one or more compounds being a hydrazine derivative. The hydrazine derivative labels carious dentin tissue selectively and substantially irreversibly in the presence of healthy dentin tissue, which is useful in the context of caries removal.
• DETECTION OF CARIOUS DENTIN TISSUE AND REMOVAL THEREOF BY MEANS OF A DENTAL INSTRUMENT
  申请人：RLS GLOBAL AB

  公开号：US20150313801A1

  公开（公告）日：2015-11-05

  The application relates to a method for testing a dental instrument comprising the steps of: a) subjecting healthy dentin tissue free from smear layer(s) to treatment with a dental instrument, thereby yielding treated dentin tissue, b) addition of a composition comprising one or more hydrazine derivative(s) to the treated dentin tissue obtained in step a), c) examining if the treated dentin tissue in step b) is stained by the one or more hydrazine derivative(s), and d) determining whether or not the treated dentin tissue contains a smear layer, wherein said one or more hydrazine derivatives is a compound of formula (I) RNHNH 2 wherein R is a chemical group containing a chromophore or forming a chromophore with NHNH 2 . Further, the application relates to a kit of parts for detection and removal of carious dentin tissue and to a method for detection and removal of carious dentin tissue.
• US9642780B2
  申请人：——

  公开号：US9642780B2

  公开（公告）日：2017-05-09