1-(1-acetyl-2H-pyrimidin-2-yl)ethanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1-(1-acetyl-2H-pyrimidin-2-yl)ethanone
• 化学式: C₈H₁₀N₂O₂
• 分子量: 166.18
• InChiKey: QCQVRCUFYKOQML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  49.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] TANNIN DERIVATIVE AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID TANNIN DERIVATIVE<br/>[FR] DÉRIVÉ DE TANNIN ET COMPOSITIONS PHARMACEUTIQUES COMPRENANT LEDIT DÉRIVÉ DE TANNIN
  申请人：SANDOZ AG

  公开号：WO2014090832A1

  公开（公告）日：2014-06-19

  The invention concerns a tannin derivative, in particular tannin derivative having antibiotic activity, obtained by covalent coupling of at least one organic acid with at least one tannin, the covalent coupling is formed as an ester or ether bond, and wherein the acid residue provides at least one functional group for covalently coupling at least one pharmaceutically active ingredient, a pharmaceutical composition comprising or consisting of said tannin derivative and a method for producing said tannin derivatives.