1,3-Dimethyl-5-{[3-(2-phenoxyethoxy)phenyl]methylidene}-1,3-diazinane-2,4,6-trione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1,3-Dimethyl-5-{[3-(2-phenoxyethoxy)phenyl]methylidene}-1,3-diazinane-2,4,6-trione
• 英文别名: 1,3-dimethyl-5-[[3-(2-phenoxyethoxy)phenyl]methylidene]-1,3-diazinane-2,4,6-trione
• 化学式: C₂₁H₂₀N₂O₅
• mdl: MFCD01873246
• 分子量: 380.4
• InChiKey: WBIOGVAICROQRZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  76.2
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• METHODS AND COMPOSITIONS FOR TARGETING C-REL
  申请人：Cornell Research Foundation, Inc.

  公开号：EP2010225A2

  公开（公告）日：2009-01-07
• Methods and Compositions for Targeting c-Rel
  申请人：Liou Hsiou-chi

  公开号：US20100055116A1

  公开（公告）日：2010-03-04

  The present invention relates to compositions and methods for targeting c-Rel. In particular, the present invention provides compositions and methods for treating cancers, inflammatory diseases, autoimmune diseases, and transplant rejection by inhibiting c-Rel activity and for regulating c-Rel for research and drug screening applications.
• [EN] METHODS AND COMPOSITIONS FOR TARGETING C-REL<br/>[FR] PROCEDES ET COMPOSITIONS DESTINES A CIBLER LE C-REL
  申请人：CORNELL RES FOUNDATION INC

  公开号：WO2007120842A2

  公开（公告）日：2007-10-25

  [EN] The present invention relates to compositions and methods for targeting c-Rel. In particular, the present invention provides compositions and methods for treating cancers, inflammatory diseases, autoimmune diseases, and transplant rejection by inhibiting c-Rel activity and for regulating c-Rel for research and drug screening applications.
  [FR] La présente invention concerne des compositions et des procédés destinés à cibler le c-Rel. L'invention porte en particulier sur des compositions et des procédés permettant de traiter les cancers, les maladies inflammatoires, les maladies auto-immunes et les rejets de greffe en inhibant l'activité c-Rel, et de réguler le c-Rel dans le cadre d'applications de recherche et de criblage de nouveaux médicaments.