8-methyl-2-oxo-4-propyl-2H-chromen-7-yl methanesulfonate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 8-methyl-2-oxo-4-propyl-2H-chromen-7-yl methanesulfonate
• 英文别名: (8-methyl-2-oxo-4-propylchromen-7-yl) methanesulfonate
• 化学式: C₁₄H₁₆O₅S
• mdl: MFCD03707095
• 分子量: 296.34
• InChiKey: SIWZGXPKBCWXJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  78
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• N-LINKED GLYCAN BIOSYNTHESIS MODULATORS
  申请人：Crawford Brett E.

  公开号：US20120100609A1

  公开（公告）日：2012-04-26

  Provided herein are N-linked glycan inhibitors, including modulators of N-linked glycan glycosylation, mannosidase, an N-linked glycan N-acetylglucosaminyl transferase, an N-linked glycan fucosyl transferase, an N-linked glycan galactosyl transferase, an N-linked glycan sialyl transferase, an N-linked glycan sulfotransferase, N-linked glycan glycophosphotransferase or a combination thereof.
• SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA
  申请人：Sirga Advanced Biopharma, Inc.

  公开号：US20150190384A1

  公开（公告）日：2015-07-09

  Disclosed herein are compounds, compositions and methods of their use to treat HIV/AIDS disease in a subject in need thereof wherein the compositions comprise small molecule inhibitors that inhibit viral preparation or viral recruitment of human tRNA3Lys.
• US9775835B2
  申请人：——

  公开号：US9775835B2

  公开（公告）日：2017-10-03