2-(4-Methoxy-2-oxochromen-3-yl)acetic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 2-(4-Methoxy-2-oxochromen-3-yl)acetic acid
• 英文别名: 2-(4-methoxy-2-oxochromen-3-yl)acetic acid
• 化学式: C₁₂H₁₀O₅
• 分子量: 234.2
• InChiKey: IEQQCNJKBVBQHU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• MODIFIED ACE2 POLYPEPTIDES
  申请人：Apeiron Biologics AG

  公开号：EP2943216A1

  公开（公告）日：2015-11-18
• Modified ACE2 polypeptides
  申请人：Apeiron Biologicals AG

  公开号：US20150353910A1

  公开（公告）日：2015-12-10

  The present invention relates to modified angiotensin converting enzyme 2 (ACE2) polypeptides and pharmaceutical and analytical uses thereof. In particular, the present invention relates to Zn 2+ depleted-, Zn 2+ free-, mixed metal- and metal ion substituted-ACE2 as well as methods for the manufacture of these variants and uses thereof, such as therapeutic and analytic uses of these ACE2 variants.
• US9757433B2
  申请人：——

  公开号：US9757433B2

  公开（公告）日：2017-09-12
• [EN] MODIFIED ACE2 POLYPEPTIDES<br/>[FR] POLYPEPTIDES ACE2 MODIFIÉS
  申请人：APEIRON BIOLOGICS AG

  公开号：WO2014108530A1

  公开（公告）日：2014-07-17

  The present invention relates to modified angiotensin converting enzyme 2 (ACE2) polypeptides and pharmaceutical and analytical uses thereof. In particular, the present invention relates to Zn2+ depleted-, Zn2+ free-, mixed metal- and metal ion substituted-ACE2 as well as methods for the manufacture of these variants and uses thereof, such as therapeutic and analytic uses of these ACE2 variants.