(9,24-Dihydroxy-16-methyl-5,17,28-trioxo-6,15,18,27-tetraoxa-2,3-dithiapentacyclo[18.8.0.04,13.07,12.021,26]octacosa-1(20),4(13),7(12),8,10,21(26),22,24-octaen-16-yl)azanium;chloride

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: (9,24-Dihydroxy-16-methyl-5,17,28-trioxo-6,15,18,27-tetraoxa-2,3-dithiapentacyclo[18.8.0.04,13.07,12.021,26]octacosa-1(20),4(13),7(12),8,10,21(26),22,24-octaen-16-yl)azanium;chloride
• 英文别名: (9,24-dihydroxy-16-methyl-5,17,28-trioxo-6,15,18,27-tetraoxa-2,3-dithiapentacyclo[18.8.0.04,13.07,12.021,26]octacosa-1(20),4(13),7(12),8,10,21(26),22,24-octaen-16-yl)azanium;chloride
• 化学式: C23H18ClNO9S2
• 分子量: 552.0
• InChiKey: PIWTZOXIXASSHN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.35
• 重原子数：
  36
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  207
• 氢给体数：
  3
• 氢受体数：
  12

文献信息

• Dithiol Compounds, Derivatives, and Uses Therefor
  申请人：Encore Health, LLC

  公开号：US20140243385A1

  公开（公告）日：2014-08-28

  Dithiol compounds and derivatives thereof are disclosed. The agents are useful for treating ocular disease, especially presbyopia and cataract. Also disclosed are novel mercaptan compounds, particularly those including a photolabile protecting group, as well as methods of using the compounds for the prevention and treatment of ocular damage and disease.

  本发明揭示了二硫化合物及其衍生物。这些药剂可用于治疗眼部疾病，特别是老视和白内障。本发明还揭示了新型巯基化合物，特别是那些包括光敏保护基的化合物，以及使用这些化合物预防和治疗眼部损伤和疾病的方法。
• US9161931B2
  申请人：——

  公开号：US9161931B2

  公开（公告）日：2015-10-20