(1R,2R)-1,2-bis(phenylselanyl)cyclopentane | 1022216-98-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (1R,2R)-1,2-bis(phenylselanyl)cyclopentane
• 英文别名: [(1R,2R)-2-phenylselanylcyclopentyl]selanylbenzene
• CAS: 1022216-98-3
• 化学式: C₁₇H₁₈Se₂
• 分子量: 380.25
• InChiKey: QFQYTNVEBMCGKE-IAGOWNOFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.81
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  硒氰酸苯酯 、 (1S)-反-1,2-环戊二醇 在 三丁基膦 作用下， 以 甲苯 为溶剂， 反应 20.0h， 以43%的产率得到(1R,2R)-1,2-bis(phenylselanyl)cyclopentane
  参考文献：
  名称：

  Novel C2-symmetric chiral ligands: enantioselective transformation of cyclic 1,2-diols into 1,2-bis(phenylsulfenyl) and 1,2-bis(phenylselenyl) derivatives

  摘要：

  Chiral C-2-symmetric S,S- and Se,Se-donating ligands as well as the C-1 mixed S,Se-donating ligands were prepared from optically active 1,2-cyclohexanediol and 1,2-cyclopentanediol via the respective S(N)2 reactions. The bis(chalcogen) ligands obtained effectively catalyze the asymmetric allylic alkylation with enantioselectivities of up to 50% ee. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2008.02.001

文献信息

• Novel C2-symmetric chiral ligands: enantioselective transformation of cyclic 1,2-diols into 1,2-bis(phenylsulfenyl) and 1,2-bis(phenylselenyl) derivatives
  作者：Elżbieta Wojaczyńska、Jacek Skarżewski

  DOI：10.1016/j.tetasy.2008.02.001

  日期：2008.3

  Chiral C-2-symmetric S,S- and Se,Se-donating ligands as well as the C-1 mixed S,Se-donating ligands were prepared from optically active 1,2-cyclohexanediol and 1,2-cyclopentanediol via the respective S(N)2 reactions. The bis(chalcogen) ligands obtained effectively catalyze the asymmetric allylic alkylation with enantioselectivities of up to 50% ee. (C) 2008 Elsevier Ltd. All rights reserved.