2,3,5-Trimethyl-6-[3-(2-methylbenzimidazol-1-yl)propyl]cyclohexa-2,5-diene-1,4-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 2,3,5-Trimethyl-6-[3-(2-methylbenzimidazol-1-yl)propyl]cyclohexa-2,5-diene-1,4-dione
• 英文别名: 2,3,5-trimethyl-6-[3-(2-methylbenzimidazol-1-yl)propyl]cyclohexa-2,5-diene-1,4-dione
• 化学式: C₂₀H₂₂N₂O₂
• 分子量: 322.4
• InChiKey: ZPBODQSJENAVBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  52
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders
  申请人：BioElectron Technology Corporation

  公开号：US10189830B2

  公开（公告）日：2019-01-29

  Disclosed herein are alkyl-heteroaryl substituted quinone derivative compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging.

  本文公开了烷基-杂芳基取代的醌衍生物化合物以及使用此类化合物治疗或抑制氧化应激紊乱（包括线粒体紊乱、能量处理受损紊乱、神经退行性疾病和衰老疾病）的方法。
• ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS
  申请人：BioElectron Technology Corporation

  公开号：EP2970158B1

  公开（公告）日：2019-02-20
• [EN] ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS<br/>[FR] DÉRIVÉS DE QUINONE À GROUPE ALKYLE-HÉTÉROARYLE SUBSTITUÉ DE TRAITEMENT DE TROUBLES DE STRESS OXYDATIF
  申请人：EDISON PHARMACEUTICALS INC

  公开号：WO2014145116A2

  公开（公告）日：2014-09-18

  Disclosed herein are alkyl-heteroaryl substituted quinone derivative compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging.