7-amino-5,11,18,22,24-pentahydroxy-13-(hydroxymethyl)-16-methyloctacyclo[13.11.1.12,10.03,8.04,25.019,27.021,26.014,28]octacosa-1(27),2(28),3(8),4,6,10,12,14,16,18,21,23,25-tridecaene-9,20-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: 7-amino-5,11,18,22,24-pentahydroxy-13-(hydroxymethyl)-16-methyloctacyclo[13.11.1.12,10.03,8.04,25.019,27.021,26.014,28]octacosa-1(27),2(28),3(8),4,6,10,12,14,16,18,21,23,25-tridecaene-9,20-dione
• 化学式: C₃₀H₁₇NO₈
• 分子量: 519.5
• InChiKey: FHUFGIHRWXJKPU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  39
• 可旋转键数：
  1
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  182
• 氢给体数：
  7
• 氢受体数：
  9

文献信息

• [EN] COMPOSITIONS AND METHODS FOR PROMOTING THE GENERATION OF ENDOCRINE CELLS<br/>[FR] COMPOSITIONS ET MÉTHODES FAVORISANT LA GÉNÉRATION DE CELLULES ENDOCRINES
  申请人：HARVARD COLLEGE

  公开号：WO2014145625A1

  公开（公告）日：2014-09-18

  Disclosed herein are compositions and methods for the generation of insulin positive β cells, for example by exposing Pdx+ pancreatic progenitor cells to one or more compounds, and compositions and kits comprising isolated populations of insulin positive cells.