5-苄基-5-丁基-2,4,6(1H,3H,5H)-嘧啶三酮 | 66941-94-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: 5-苄基-5-丁基-2,4,6(1H,3H,5H)-嘧啶三酮
• 英文名称: 5-benzyl-5-butyl-barbituric acid
• 英文别名: 5-Benzyl-5-butyl-barbitursaeure；Benzylbutylbarbiturate；5-benzyl-5-butyl-1,3-diazinane-2,4,6-trione
• CAS: 66941-94-4
• 化学式: C₁₅H₁₈N₂O₃
• 分子量: 274.32
• InChiKey: XDNQMQVXDKJOET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  75.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• COMPOSITIONS AND METHODS FOR THE TREATMENT OF SUBSTANCE USE DISORDERS, ADDICTION, AND PSYCHIATRIC DISORDERS
  申请人：Embera Neurotherapeutics, Inc.

  公开号：EP3310358A1

  公开（公告）日：2018-04-25
• OZONOLYSIS FOR ACTIVATION OF COMPOUNDS AND DEGRADATION OF OZONE
  申请人：Air Cross Inc.

  公开号：EP3349893A1

  公开（公告）日：2018-07-25
• Multipurpose Device
  申请人：Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center

  公开号：US20210038842A1

  公开（公告）日：2021-02-11

  A multipurpose device for preventing or treating deep vein thrombosis, extremity edema, and breathing conditions is provided herein. The multipurpose device includes a respiratory device, such as a flutter valve or a spirometer, having a mouthpiece or nasal breathing piece, a pump connected to the respiratory device by first tubing, a release valve connected to the pump by second tubing, and one or more third tubing(s) connected to the release valve.
• [EN] COMPOSITIONS AND METHODS FOR THE TREATMENT OF SUBSTANCE USE DISORDERS, ADDICTION, AND PSYCHIATRIC DISORDERS<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR LE TRAITEMENT DE TROUBLES D'UTILISATION DE SUBSTANCES, D'ACCOUTUMANCE, ET DE TROUBLES PSYCHIATRIQUES
  申请人：EMBERA NEUROTHERAPEUTICS INC

  公开号：WO2016209929A1

  公开（公告）日：2016-12-29

  The present invention features a composition comprising a first agent and a second agent for treating disorder associated with aberrant activity in the HPA axis like an addiction to a substance (e.g., cocaine, amphetamines, methamphetamine, methylphenidate, heroin, coedine, hydrocodone, nicotine, alcohol, prescription medication (e.g., Percodan®, Percoset®), marijuana, tobacco, methadone, food), addiction to an activity (e.g., gambling, sex, eating), substance use disorders, mood disorders, anxiety disorders, bipolar disorder, sleep disorders, insomnia, posttraumatic stress syndrome, borderline personality disorder, disruptive behavior disorders, ADHD, major depressive disorder, burnout, chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome, eating disorders (e.g., Prader Willi Syndrome), obesity, depression, menopause, prementsrual syndrome (PMS), obsessive compulsive disorder (OCD), social anxiety, generalized anxiety disorder, dysthymia, or schizophrenia.
• [EN] MULTIPURPOSE DEVICE<br/>[FR] DISPOSITIF POLYVALENT
  申请人：INSTITUTE FOR CANCER RES D/B/A THE RES INSTITUTE OF FOX CHASE CANCER CENTER

  公开号：WO2019152296A1

  公开（公告）日：2019-08-08

  A multipurpose device for preventing or treating deep vein thrombosis, extremity edema, and breathing conditions is provided herein. The multipurpose device includes a respiratory device, such as a flutter valve or a spirometer, having a mouthpiece or nasal breathing piece, a pump connected to the respiratory device by first tubing, a release valve connected to the pump by second tubing, and one or more third tubing(s) connected to the release valve.