N-(1,3-dihydrobenzimidazol-2-ylidene)-4-phenoxybutanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: N-(1,3-dihydrobenzimidazol-2-ylidene)-4-phenoxybutanamide
• 化学式: C₁₇H₁₇N₃O₂
• 分子量: 295.34
• InChiKey: YMCXJDMPCASFHB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  67
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• COMPOUNDS AS RORyT MODULATORS AND USES THEREOF
  申请人：Littman Dan

  公开号：US20130065842A1

  公开（公告）日：2013-03-14

  Heterocyclic compounds, and pharmaceutical compositions thereof, are disclosed as RORγt modulators that have a formula represented by the following: and wherein n1, n2, R 1 , R 2 , R 3 , and R 4 are as described herein. These compounds may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
• US9101600B2
  申请人：——

  公开号：US9101600B2

  公开（公告）日：2015-08-11