Salicylsaeure-<2-pyridyl-(2)-ethylamid> | 107620-31-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Salicylsaeure-<2-pyridyl-(2)-ethylamid>
• 英文别名: 2-hydroxy-N-(2-pyridylethyl)benzamide；N-(2-[2]pyridyl-ethyl)-salicylamide；N-(2-[2]Pyridyl-aethyl)-salicylamid；2-hydroxy-N-(2-pyridin-2-ylethyl)benzamide
• CAS: 107620-31-5
• 化学式: C₁₄H₁₄N₂O₂
• 分子量: 242.277
• InChiKey: LNBTVGCBNIASFK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  62.2
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  甲醇 、 Salicylsaeure-<2-pyridyl-(2)-ethylamid> 、 copper(II) bis(trifluoromethanesulfonate) 在 triethylamine 作用下， 以 甲醇 为溶剂， 以68%的产率得到[copper(II)2(2-hydroxy-N-(2-pyridylethyl)benzamide-2H)2(methanol)2]
  参考文献：
  名称：

  Syntheses and structures of a phenoxo-bridged copper(II) distorted cubane and related complexes with 2-hydroxy-N-(2-pyridylalkyl)benzamide ligands

  摘要：

  Two new pyridylalkylamide ligands containing phenol groups appended to the amide, 2-hydroxy-N-(2-pyridylmethyl)benzamide (HLPhOH) and 2-hydroxy-N-(2-pyridylethyl)benzamide (HLPhOH'), were synthesized. Copper(II) complexes of these ligands were synthesized and characterized by X-ray crystallography, ESI-MS, FTIR, UV/Vis, and EPR spectroscopy. When basic Et3N was used to deprotonate the ligands, tetra-copper(II) [Cu-4(L-PhO)(4)] (1) or dicopper(II) [Cu-2(L-PhO')(2)(CH3OH)(2)] (3) were formed. When base was not used, mononuclear [Cu(HLPhOH)(2)Cl-2] (2) resulted. Complex 1 possesses a distorted cubane-like structure, with the ligands bridging via the phenoxo oxygen atoms, and the copper atoms possessing a distorted square planar geometry. The ligands in dimeric complex 3 also bridge between copper( II) atoms via the phenoxo oxygen atoms, and the copper atoms are square pyramidal. Monomeric 2 is a tetragonally distorted six-coordinate species with pyridyl N atoms and chloride ligands in the equatorial plane, and long interactions with the amide carbonyl O atoms in the axial positions. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2009.04.007
• 作为产物：
  描述：

  2-乙烯基吡啶 在 sodium hydroxide 作用下， 生成 Salicylsaeure-<2-pyridyl-(2)-ethylamid>
  参考文献：
  名称：

  Pyridylethylated Benzoxazinediones¹

  摘要：

  DOI：

  10.1021/ja01568a039

文献信息

• Pyridylethylated Benzoxazinediones¹
  作者：Seymour L. Shapiro、Ira M. Rose、Louis Freedman

  DOI：10.1021/ja01568a039

  日期：1957.6
• Syntheses and structures of a phenoxo-bridged copper(II) distorted cubane and related complexes with 2-hydroxy-N-(2-pyridylalkyl)benzamide ligands
  作者：Zhaodong Wang、Douglas R. Powell、Robert P. Houser

  DOI：10.1016/j.inoche.2009.04.007

  日期：2009.6

  Two new pyridylalkylamide ligands containing phenol groups appended to the amide, 2-hydroxy-N-(2-pyridylmethyl)benzamide (HLPhOH) and 2-hydroxy-N-(2-pyridylethyl)benzamide (HLPhOH'), were synthesized. Copper(II) complexes of these ligands were synthesized and characterized by X-ray crystallography, ESI-MS, FTIR, UV/Vis, and EPR spectroscopy. When basic Et3N was used to deprotonate the ligands, tetra-copper(II) [Cu-4(L-PhO)(4)] (1) or dicopper(II) [Cu-2(L-PhO')(2)(CH3OH)(2)] (3) were formed. When base was not used, mononuclear [Cu(HLPhOH)(2)Cl-2] (2) resulted. Complex 1 possesses a distorted cubane-like structure, with the ligands bridging via the phenoxo oxygen atoms, and the copper atoms possessing a distorted square planar geometry. The ligands in dimeric complex 3 also bridge between copper( II) atoms via the phenoxo oxygen atoms, and the copper atoms are square pyramidal. Monomeric 2 is a tetragonally distorted six-coordinate species with pyridyl N atoms and chloride ligands in the equatorial plane, and long interactions with the amide carbonyl O atoms in the axial positions. (C) 2009 Elsevier B.V. All rights reserved.