7-cyclohexyl-5-(pyridin-2-yl)pyrido[2,3-d]pyridazine-8(7H)-thione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 7-cyclohexyl-5-(pyridin-2-yl)pyrido[2,3-d]pyridazine-8(7H)-thione
• 英文别名: 7-Cyclohexyl-5-pyridin-2-ylpyrido[2,3-d]pyridazine-8-thione；7-cyclohexyl-5-pyridin-2-ylpyrido[2,3-d]pyridazine-8-thione
• 化学式: C₁₈H₁₈N₄S
• 分子量: 322.434
• InChiKey: HYFLEPJAGGZPAF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  73.5
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Rilyazine Derivatives and Compositions for The Treatment of Cancer
  申请人：Warner Babcock Institute For Green Chemistry, LLC

  公开号：US20150065510A1

  公开（公告）日：2015-03-05

  The present application discloses Rilyazine analogs, methods for their preparation, and the treatment of cancer by the administration of an effective amount of the Rilyazine analogs to a patient in need thereof.

  本申请公开了Rilyazine类似物，它们的制备方法，以及通过向需要治疗的患者施用有效剂量的Rilyazine类似物来治疗癌症。
• RILYAZINE DERIVATIVES AND COMPOSITIONS FOR THE TREATMENT OF CANCER
  申请人：The Warner-Babcock Institute For Green Chemistry LLC

  公开号：EP3041840B1

  公开（公告）日：2018-02-28
• US9394299B2
  申请人：——

  公开号：US9394299B2

  公开（公告）日：2016-07-19
• [EN] RILYAZINE DERIVATIVES AND COMPOSITIONS FOR THE TREATMENT OF CANCER<br/>[FR] DÉRIVÉS DE RILYAZINE ET COMPOSITIONS POUR LE TRAITEMENT D'UN CANCER
  申请人：WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC

  公开号：WO2015034785A1

  公开（公告）日：2015-03-12

  The present application discloses Rilyazine analogs, methods for their preparation, and the treatment of cancer by the administration of an effective amount of the Rilyazine analogs to a patient in need thereof.