5,5-dimethyl-2,4-dimethoxy-4-phenyl-2-imidazoline 1-oxyl | 120341-47-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5,5-dimethyl-2,4-dimethoxy-4-phenyl-2-imidazoline 1-oxyl
• CAS: 120341-47-1
• 化学式: C₁₃H₁₇N₂O₃
• 分子量: 249.29
• InChiKey: MBFNKQINOIUXMB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  35.1
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5,5-dimethyl-2,4-dimethoxy-4-phenyl-2-imidazoline 1-oxyl 在 氯化铵 、 锌 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  Reduction of α,α-dialkoxy-substituted nitroxides: the synthesis of α-alkoxynitrones and acetals ofN-hydroxyamides

  摘要：

  Reduction of stable nitroxides derived from tetrahydrooxazole, tetrahydroimidazole, 2,5-dihydroimidazole, and 2,5-dihydroimidazole 3-oxide containing alkoxy groups in alpha-position to the nitroxyl group affords alpha-alkoxynitrones, acetals of N-hydroxyamides, or their equilibrium mixtures.

  DOI：

  10.1007/bf02494863
• 作为产物：
  描述：

  甲醇 、 1H-Imidazole, 2,5-dihydro-1-hydroxy-5,5-dimethyl-4-phenyl- 在 lead dioxide 作用下， 反应 5.0h， 以65%的产率得到5,5-dimethyl-2,4-dimethoxy-4-phenyl-2-imidazoline 1-oxyl
  参考文献：
  名称：

  Oxidative alkoxylation of 4H-imidazole N-oxides as a new method of synthesis of stable nitroxyl radicals of the 2- and 3-imidazoline series with alkoxy groups at the ?-carbon atom of the radical center

  摘要：

  DOI：

  10.1007/bf00978444

文献信息

• Reduction of α,α-dialkoxy-substituted nitroxides: the synthesis of α-alkoxynitrones and acetals ofN-hydroxyamides
  作者：S. M. Bakunova、I. A. Grigor'ev、I. A. Kirilyuk、L. B. Voldarsky

  DOI：10.1007/bf02494863

  日期：1999.11

  Reduction of stable nitroxides derived from tetrahydrooxazole, tetrahydroimidazole, 2,5-dihydroimidazole, and 2,5-dihydroimidazole 3-oxide containing alkoxy groups in alpha-position to the nitroxyl group affords alpha-alkoxynitrones, acetals of N-hydroxyamides, or their equilibrium mixtures.
• Oxidative alkoxylation of 4H-imidazole N-oxides as a new method of synthesis of stable nitroxyl radicals of the 2- and 3-imidazoline series with alkoxy groups at the ?-carbon atom of the radical center
  作者：I. A. Grigor'ev、I. A. Kirilyuk、V. F. Starichenko、L. B. Volodarskii

  DOI：10.1007/bf00978444

  日期：1989.7