4-Methyl-phthalic acid di-tert-butyl ester | 536711-07-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Methyl-phthalic acid di-tert-butyl ester
• 英文别名: Ditert-butyl 4-methylbenzene-1,2-dicarboxylate
• CAS: 536711-07-6
• 化学式: C₁₇H₂₄O₄
• 分子量: 292.375
• InChiKey: JZKNMHHSWIVXJW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-Methyl-phthalic acid di-tert-butyl ester 在 N-溴代丁二酰亚胺(NBS) 、 过氧化苯甲酰 作用下， 以 四氯化碳 为溶剂， 反应 7.0h， 生成
  参考文献：
  名称：

  Parallel Synthesis of Glycomimetic Libraries:  Targeting a C-Type Lectin

  摘要：

  graphicWe have developed methods for the parallel synthesis of two libraries of non-carbohydrate-based analogues of mannose on a solid support. The natural product shikimic acid-was used as a key building block. The ability of the compounds to block the binding of the C-type lectin MBP-A to a mannosylated surface was assessed in a high-throughput assay. Ten library members with inhibitory activities equivalent to that of alpha-methyl mannopyranoside were identified.

  DOI：

  10.1021/ol0340383
• 作为产物：
  描述：

  4-甲基邻苯二甲酸 、 异丁烯 在 硫酸 作用下， 以 二氯甲烷 为溶剂， 反应 96.0h， 生成 4-Methyl-phthalic acid di-tert-butyl ester
  参考文献：
  名称：

  Parallel Synthesis of Glycomimetic Libraries:  Targeting a C-Type Lectin

  摘要：

  graphicWe have developed methods for the parallel synthesis of two libraries of non-carbohydrate-based analogues of mannose on a solid support. The natural product shikimic acid-was used as a key building block. The ability of the compounds to block the binding of the C-type lectin MBP-A to a mannosylated surface was assessed in a high-throughput assay. Ten library members with inhibitory activities equivalent to that of alpha-methyl mannopyranoside were identified.

  DOI：

  10.1021/ol0340383

文献信息

• SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST
  申请人：Toho Titanium Co., Ltd.

  公开号：EP1260524A1

  公开（公告）日：2002-11-27

  The solid catalyst component for polymerization of olefins comprising (a) a magnesium compound, (b) titanium tetrachloride, (c) a phthalic acid diester or a derivative thereof, and (d1) a hydroxy group-containing hydrocarbon compound having a specific structure or (d2) a mercapto group-containing hydrocarbon compound having a specific structure and the olefin polymerization catalyst can produce olefin polymers in a very high yield, particularly can produce propylene polymers in a very high yield, while retaining high stereoregularity.

  用于烯烃聚合的固体催化剂组分包括：(a) 镁化合物；(b) 四氯化钛；(c) 邻苯二甲酸二酯或其衍生物；(d1) 具有特定结构的含羟基烃化合物或 (d2) 具有特定结构的含巯基烃化合物，该烯烃聚合催化剂能以极高的产率生产烯烃聚合物，特别是能以极高的产率生产丙烯聚合物，同时保持较高的立体规整性。
• Solid catalyst component for olefin polymerization and catalyst
  申请人：——

  公开号：US20040072681A1

  公开（公告）日：2004-04-15

  A solid catalyst component for olefin polymerization characterized by being formed from (a) a magnesium compound, (b) titanium tetrachloride, (c) a phthalic diester and a derivative thereof, and either (d 1 ) a hydroxylated hydrocarbon compound (phenol, etc.) represented by a specific formula or (d 2 ) a mercapto-containing hydrocarbon compound (thiophenol, etc.) represented by a specific formula. With a catalyst obtained from this solid catalyst component, an olefin polymer can be obtained in extremely high yield. In particular, a propylene polymer which retains high stereoregularity can be obtained in extremely high yield

  一种用于烯烃聚合的固体催化剂组分，其特征在于它是由(a)镁化合物，(b)四氯化钛，(c)邻苯二甲酸二酯及其衍生物，以及(d) 1 以特定公式表示的羟基烃化合物（苯酚等），或 (d 1) 2 ) 一种由特定公式表示的含巯基的烃化合物（噻吩酚等）。使用由这种固体催化剂组分制成的催化剂，可以获得产量极高的烯烃聚合物。特别是可以获得一种立体规整度很高的丙烯聚合物，产量极高
• US6878659B2
  申请人：——

  公开号：US6878659B2

  公开（公告）日：2005-04-12
• Parallel Synthesis of Glycomimetic Libraries:  Targeting a C-Type Lectin
  作者：Michael C. Schuster、David A. Mann、Tonia J. Buchholz、Kathryn M. Johnson、William D. Thomas、Laura L. Kiessling

  DOI：10.1021/ol0340383

  日期：2003.5.1

  graphicWe have developed methods for the parallel synthesis of two libraries of non-carbohydrate-based analogues of mannose on a solid support. The natural product shikimic acid-was used as a key building block. The ability of the compounds to block the binding of the C-type lectin MBP-A to a mannosylated surface was assessed in a high-throughput assay. Ten library members with inhibitory activities equivalent to that of alpha-methyl mannopyranoside were identified.