4-(4-methylphenyl)phenethyl alcohol | 131306-69-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(4-methylphenyl)phenethyl alcohol
• 英文别名: 2-(4'-Methyl-[1,1'-biphenyl]-4-yl)ethanol；2-[4-(4-methylphenyl)phenyl]ethanol
• CAS: 131306-69-9
• 化学式: C₁₅H₁₆O
• 分子量: 212.291
• InChiKey: FOSIQUKJICCVTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  potassium [4-(2-hydroxyethyl)phenyl]trifluoroborate 、 对溴甲苯 在 palladium diacetate 、 potassium carbonate 作用下， 以 甲醇 为溶剂， 反应 0.08h， 以88%的产率得到4-(4-methylphenyl)phenethyl alcohol
  参考文献：
  名称：

  A Facile One-Pot Preparation of Potassium Hydroxyaryl- and (Hydroxyalkyl)aryltrifluoroborates

  摘要：

  Potassium hydroxyaryl- and (hydroxyalkyl)aryltrifluoroborates have been prepared in a simple one-pot process from the corresponding hydroxy-substituted aryl halides in 51-98% yields through an in situ protection of the free hydroxyl group with t-BuLi. Also, we successfully performed a microwave-promoted Suzuki-Miyaura cross-coupling reaction of these substrates with aryl- and alkenyl bromides in the presence of 0.5 mol % of Pd(OAc)(2) catalyst without ligands.

  DOI：

  10.1021/ol800083j

文献信息

• LIQUID-CRYSTALLINE MEDIUM
  申请人：Archetti Graziano

  公开号：US20140138581A1

  公开（公告）日：2014-05-22

  The invention relates to a liquid-crystalline medium based on a mixture of polar compounds having a negative dielectric anisotropy which contains at least one self-aligning additive, especially at least one additive selected from the group of the compounds of the formula IA to ID in which R 1A , R 1B , R 1C , L 1-12 , R 1D , Ring I, u, v, w, x, y, z and m have the meanings indicated in Claim 4 and to the use thereof for an active-matrix display, in particular based on the VA, PSA and PS-VA effect in LC displays.
• US9234136B2
  申请人：——

  公开号：US9234136B2

  公开（公告）日：2016-01-12