2,3,4,5-tetrafluoro-6-methylbenzenethiol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚类
• 英文名称: 2,3,4,5-tetrafluoro-6-methylbenzenethiol
• 英文别名: 2,3,4,5-Tetrafluoro-6-methylbenzenethiol
• 化学式: C₇H₄F₄S
• 分子量: 196.168
• InChiKey: XCXUHIINVFSJQF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,3,4,5-tetrafluoro-6-methylbenzenethiol 在 三乙酰氧基硼氢化钠 作用下， 生成 N-(3-phenoxybenzyl)-6-((2,3,4,5-tetrafluoro-6-methylphenyl)sulfonyl)pyridin-2-amine
  参考文献：
  名称：

  BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF

  摘要：

  Provided herein are benzenesulfonamide compounds, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.

  公开号：

  US20240018153A1

文献信息

• CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS
  申请人：Trustees of Boston College

  公开号：US20140371454A1

  公开（公告）日：2014-12-18

  The present application provides, among other things, compounds and methods for metathesis reactions. In some embodiments, provided compounds promote highly efficient and highly Z-selective metathesis. In some embodiments, provided compounds and methods are particularly useful for producing allyl alcohols. In some embodiments, provided compounds have the structure of formula I. In some embodiments, provided compounds comprise ruthenium, and a ligand bonded to ruthenium through a sulfur atom.

  本申请提供了化合物和用于交换反应的方法，其中所提供的化合物在某些实施方式中促进高效和高度Z-选择性的交换反应。在某些实施方式中，所提供的化合物和方法特别适用于生产烯丙醇。在某些实施方式中，所提供的化合物具有式I的结构。在某些实施方式中，所提供的化合物包含钌，并且与钌通过硫原子结合的配体。
• US9938253B2
  申请人：——

  公开号：US9938253B2

  公开（公告）日：2018-04-10
• [EN] BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS DE BENZÈNESULFONAMIDE ET LEURS UTILISATIONS
  申请人：2692372 ONTARIO INC

  公开号：WO2021009568A1

  公开（公告）日：2021-01-21

  Provided herein are benzenesulfonamide derivatives having Formula (III), pharmaceutical compositions comprising said compounds, and method for using said compounds for disrupting proteins/polypeptides, protein/polypeptide function, and for the treatment of diseases through the disruption of proteins or polypeptides involved in the etiology of the disease. Said compounds comprise fluorinated benzene sulfonamide structures.
• BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
  申请人：2692372 ONTARIO, INC.

  公开号：US20240018153A1

  公开（公告）日：2024-01-18

  Provided herein are benzenesulfonamide compounds, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.